How much is the bus ticket from Florence to Chicago?

The cheapest bus tickets from Florence to Chicago start from $162. The average price for this route is around $223. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Florence to Chicago?

The average bus travel time from Florence to Chicago is 1d 3h, covering a distance of 1097 km. The quickest bus can get you there in 1d and is operated by Greyhound .

Which bus companies service the Florence to Chicago route?

Several major bus companies operate on this route with 11 buses available per day, including services from Greyhound , FlixBus .

What are the earliest and latest departure times for the bus from Florence to Chicago?

The earliest bus departs from Florence to Chicago at 12:05am. And the latest bus departs at 4:30pm.

What are the CO₂ emissions for the bus trip from Florence to Chicago?

A bus trip from Florence to Chicago generates an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Florence to Chicago?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87500 reviews.

Which bus company has the best Wi-Fi from Florence to Chicago?

Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

Which bus company has the best on-time performance from Florence to Chicago?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Florence to Chicago?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Florence to Chicago from $152 | Refundable Tickets

Next bus departures

Next departures for Florence to Chicago on January 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	4:10pm	Bus station	1d	3:55pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	4:10pm	Bus station	1d	3:15pm	Downtown Greyhound Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	1d 8h	12:10am	Downtown Greyhound Station	No tags
	Bus	4:30pm	Bus station	1d 16h	8:00am	537-517 W. Jackson Blvd	No tags

Next departures for Florence to Chicago on January 19
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	4:10pm	Bus station	1d 1h	5:05pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	4:10pm	Bus station	1d	3:15pm	Downtown Greyhound Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	1d	11:30am	Downtown Greyhound Station	No tags
	Bus	11:55am	Bus station	1d 3h	2:10pm	537-517 W. Jackson Blvd	No tags
Greyhound Lines, Inc. + FlixBus	Bus	4:30pm	Bus station	1d 8h	12:10am	Downtown Greyhound Station	No tags

Last refresh of the prices: Last Friday at 11:07 AM EST.

Compare 2 ways to go from Florence to Chicago

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Chicago. The journey takes about 1 day, 3 hours 15 minutes, and with fares starting at just $162, it presents an excellent value for a comfortable ride.

11bus per day

1d 3hAverage Duration

1097 kmDistance

27kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$162 - $679	Average Duration1d 3h	CO₂ emissions 27kg CO₂e
Train	Average Price$309 - $3,837	Average Duration1d 11h	CO₂ emissions 100kg CO₂e

Where are the popular stops in Florence and Chicago?

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page Map
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Map

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page Map
B
Chicago O'Hare International Airport
Visit page Map
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
Map
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
Map
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
Map
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Map

Compare bus companies

Greyhound

3.5/587,508 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/512,086 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Florence, SC, US to Chicago by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Florence to Chicago?
The cheapest bus tickets from Florence to Chicago start from $162. The average price for this route is around $223. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Chicago?
The average bus travel time from Florence to Chicago is 1d 3h, covering a distance of 1097 km. The quickest bus can get you there in 1d and is operated by Greyhound.
Which bus companies service the Florence to Chicago route?
Several major bus companies operate on this route with 11 buses available per day, including services from Greyhound, FlixBus.
What are the earliest and latest departure times for the bus from Florence to Chicago?
The earliest bus departs from Florence to Chicago at 12:05am. And the latest bus departs at 4:30pm.
What are the CO₂ emissions for the bus trip from Florence to Chicago?
A bus trip from Florence to Chicago generates an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Florence to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Florence to Chicago?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Florence to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01-16

$188

01-17

$187

Today

$187

01-19

$182

01-20

$172

01-21

$169

01-22

$170

01-23

$166

The cheapest trip from Florence, SC, US to Chicago was searched and found on Jan 23, 2026 with a price of $166

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Chicago, as early as possible.

You can expect to pay from $166 to $325 for a bus ticket from Florence, SC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $166 which is on 2026-01-23.