Cheap buses leaving tomorrow
One passenger / one way
- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: Fastest
- Departure time: August 10 atDeparture city: FlorenceDeparture location: Bus stationArrival time: August 11 atDestination city: ChicagoDestination location: Chicago 95Th & Dan RyanOperated by: FlixBus
Vehicle: BusDuration:
Last refresh of the prices: Last Sunday at 3:43 PM EDT.
Prices and availability are subject to change.
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Compare 2 ways to go from Florence to Chicago
Busbud recommends taking the bus from Florence to ChicagoAmong the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 6 hours 35 minutes, and with fares starting at just US$108, it presents an excellent value for a comfortable ride.
Bus Florence, SC, US to Chicago: Trip Overview
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Florence to Chicago Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Chicago.
We make sure you can find a bus service from Florence to Chicago from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses travelling from Florence to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Florence and Chicago?
Frequently asked questions on the trip Florence, SC, US - Chicago
How much does a bus ticket from Florence to Chicago cost?
The bus ticket price from Florence to Chicago starts at US$108. The best way to find cheap bus tickets from Florence to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Florence to Chicago?
The average travel time between Florence and Chicago is around 1d 6h, although the fastest bus will take about 1d 3h.This is the time it takes to travel the 1102 km that separates the two cities.
How many daily bus connections are there between Florence and Chicago?
The number of buses from Florence to Chicago can differ depending on the day of the week. On average, there are 10 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Florence to Chicago by comparing and selecting the bus that fits you travel style and budget on Busbud.
Which bus companies travel from Florence to Chicago?
When taking the bus from Florence to Chicago, you can travel comfortably and safely with FlixBus, Greyhound.
What are the departure and arrival stations when taking the bus from Florence to Chicago?
Buses travelling between Florence and Chicago leave from Florence Bus Station or TA Travel Center - Florence and arrive at Downtown Greyhound Station, Chicago O'Hare International Airport, Polk St & Canal St.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Chicago was searched and found on Aug 8, 2025 with a price of US$156To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Chicago, as early as possible.
You can expect to pay from US$156 to US$161 for a bus ticket from Florence, SC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$157 which is on 2025-08-11.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Chicago but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Florence to Chicago, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Chicago that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Florence to Chicago.
Did you know?
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
What's the cheapest way to go from Florence, SC, US to Chicago?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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