Find coaches from Florence, SC, US to Chicago

Previously seen journeys

Next departures from Florence to Chicago on 11 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Bus
Bus station
Chicago 95Th & Dan RyanNo tags
FlixBus + Greyhound
Bus
Bus station
Downtown Greyhound StationNo tags
FlixBus + Greyhound
Bus
Bus station
Chicago 95Th & Dan RyanNo tags
Greyhound + FlixBus
Bus
Bus station
Downtown Greyhound StationNo tags
GreyhoundBus
Bus station
Downtown Greyhound StationNo tags

Compare 2 ways to travel from Florence to Chicago

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 5 hours 5 minutes and with fares starting at just R 1 937, it presents an excellent value for a comfortable ride.

7bus per day
1d 5hAverage duration
1098 kmDistance
27kgCO₂ emissions
Bus
Average priceR 1 937 - R 6 228Average duration1d 5h
27kg CO₂e
Train
Average priceR 3 261 - R 30 433Average duration1d 11h
100kg CO₂e

Frequently asked questions about travelling from Florence, SC, US to Chicago by bus

  1. How much does a bus ticket from Florence to Chicago cost?

    The bus ticket price from Florence to Chicago starts at R 1 937. The best way to find cheap bus tickets from Florence to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Florence to Chicago?

    The average travel time between Florence and Chicago is around 1d 5h, although the fastest bus will take about 23h 10m. This is the time it takes to travel the 1102 km that separates the two cities.

  3. How many daily bus connections are there between Florence and Chicago?

    The number of buses from Florence to Chicago can differ depending on the day of the week. On average, there are 7 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Florence to Chicago by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Florence to Chicago?

    When taking the bus from Florence to Chicago, you can travel comfortably and safely with Greyhound, FlixBus.

  5. What are the departure and arrival stations when taking the bus from Florence to Chicago?

    Buses travelling between Florence and Chicago leave from Florence Bus Station or TA Travel Center - Florence and arrive at Downtown Greyhound Station, Chicago O'Hare International Airport, Polk St & Canal St.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/11
R 2 699
10/11
R 2 453
Today
No data
12/11
No data
13/11
No data
14/11
No data
15/11
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16/11
No data
busbud logoThe cheapest trip from Florence, SC, US to Chicago was searched and found on 10 Nov 2025 with a price of R 2 453

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Chicago as early as possible.

What's the cheapest way to go from Florence, SC, US to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

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