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- This trip is recommended because it is the: Cheapest + FastestDeparture time: June 21 atDeparture city: Des MoinesDeparture location: Des Moines (Subway)Arrival time: June 22 atDestination city: NashvilleDestination location: Greyhound Bus StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Last refresh of the prices: Last Tuesday at 6:20 PM CDT.
Prices and availability are subject to change.
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Bus Des Moines to Nashville: Trip Overview
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Des Moines to Nashville Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Des Moines to Nashville.
We make sure you can find a bus service from Des Moines to Nashville from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses travelling from Des Moines to Nashville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Des Moines and Nashville?
Frequently asked questions on the trip Des Moines - Nashville, TN
How far is Des Moines from Nashville?
It's about 846 km (525 miles) from Des Moines to Nashville.
What are the departure and arrival locations for buses traveling from Des Moines to Nashville?
Buses departing from Jefferson/Trailways Depot in Des Moines will take you to Greyhound Bus Station in Nashville.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Nashville was searched and found on Jun 18, 2025 with a price of US$120To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Nashville, as early as possible.
You can expect to pay from US$120 to US$225 for a bus ticket from Des Moines to Nashville based on the last 2 days. You can expect to find the cheapest price for the trip at US$152 which is on 2025-06-21.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Des Moines to Nashville but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Des Moines to Nashville, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Des Moines to Nashville that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Des Moines to Nashville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Top travelled bus routes
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Popular Buses Connecting Des Moines
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