Bus Tickets from Cincinnati to Greenville, SC

Next departures

Next departures for Cincinnati to Greenville on October 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Cincinnati Bus Station
1116 Woodruff RdCheapest
Greyhound Lines, Inc. + FlixBus
Cincinnati Bus Station
1116 Woodruff RdFastest
Greyhound Lines, Inc. + FlixBus
Cincinnati Bus Station
1116 Woodruff RdNo tags
Greyhound Lines, Inc.
Cincinnati Bus Station
1116 Woodruff RdNo tags
Greyhound Lines, Inc.
Cincinnati (Downtown)
1116 Woodruff RdNo tags

Last refresh of the prices: Yesterday at 8:30 PM EDT.

Accepted payments

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Compare 2 ways to go from Cincinnati to Greenville

Bus
Average PriceUS$69 - US$177Average Duration19h
13kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$146 - US$1,034Average Duration1d 1h
46kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Cincinnati to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 19 hours, and with fares starting at just US$69, it presents an excellent value for a comfortable ride.

4bus per day
19hAverage Duration
US$69Cheapest ticket
13kgCO₂ emissions

Bus Cincinnati to Greenville, SC: Trip Overview

Average Ticket PriceUS$95
Average Bus Trip Duration19h
Number of daily buses4
Earliest bus departure12:55am
Distance523 km
Latest bus departure5:30pm

Cincinnati to Greenville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Cincinnati to Greenville.

We make sure you can find a bus service from Cincinnati to Greenville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from Cincinnati, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Cincinnati - Greenville, SC

  1. How far is Cincinnati from Greenville?

    It's about 514 km (319 miles) from Cincinnati to Greenville.

  2. What are the departure and arrival locations for buses traveling from Cincinnati to Greenville?

    Buses departing from Greyhound Station in Cincinnati will take you to Guadalajara Supermarket Bus Stop in Greenville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-28
No data
09-29
US$150
Today
US$74
10-01
US$72
10-02
No data
10-03
No data
10-04
No data
10-05
No data
busbud logoThe cheapest trip from Cincinnati to Greenville, SC was searched and found on Oct 1, 2025 with a price of US$72

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cincinnati to Greenville, SC, as early as possible.

You can expect to pay from US$72 to US$169 for a bus ticket from Cincinnati to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$72 which is on 2025-10-01.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Cincinnati to Greenville but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Cincinnati to Greenville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Cincinnati to Greenville.

Tune out to the fine sounds of your best music playlist on your bus trip from Cincinnati to Greenville while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Cincinnati to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Cincinnati by bus?

Bus from Greenville, SC to Cincinnati

You can also go to Greenville, SC by train

Train from Cincinnati to Greenville, SC

Why choose Busbud?

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