Bus Tickets from Charleston, SC, US to Port Saint Lucie

Bus Charleston, SC, US to Port Saint Lucie: Trip Overview

Average Ticket PriceUS$114
Average Bus Trip Duration12h
Number of daily buses1
Earliest bus departure3:15pm
Distance625 km

Charleston to Port Saint Lucie Bus

With Busbud, comparing and booking tickets for a bus from Charleston to Port Saint Lucie is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Charleston to Port Saint Lucie will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Charleston to Port Saint Lucie, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Charleston, SC, US - Port Saint Lucie

  1. What is the travel distance from Charleston to Port Saint Lucie?

    The distance covered from Charleston to Port Saint Lucie is 613 km (380 miles).

  2. What are the departure and arrival locations for buses traveling from Charleston to Port Saint Lucie?

    Buses traveling this route start their trip at Charleston Bus Station, in Charleston, and end it at Port St Lucie Mobil Gas Bus Stop, in Port Saint Lucie.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-08
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09-09
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Today
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09-11
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09-12
US$99
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busbud logoThe cheapest trip from Charleston, SC, US to Port Saint Lucie was searched and found on Sep 12, 2025 with a price of US$99

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Port Saint Lucie, as early as possible.

You can expect to pay from US$99 to US$99 for a bus ticket from Charleston, SC, US to Port Saint Lucie based on the last 2 days. You can expect to find the cheapest price for the trip at US$99 which is on 2025-09-12.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Charleston to Port Saint Lucie.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Charleston to Port Saint Lucie, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Charleston to Port Saint Lucie that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Charleston to Port Saint Lucie, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Charleston, SC, US by bus?

Bus from Port Saint Lucie to Charleston, SC, US

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