Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Appleton | Downtown Greyhound Station | CheapestFastest | |||||
 | Appleton | Chicago (Union Station), IL | No tags | |||||
| Appleton | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Today at 7:22 PM CST.
Get from Appleton to Chicago
The journey takes about 4 hours 30 minutes, and with fares starting at just $41, it presents an excellent value for a comfortable ride.
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Frequently asked questions about travelling from Appleton to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Appleton to Chicago?
The cheapest bus tickets from Appleton to Chicago start from $41. The average price for this route is around $63. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Appleton to Chicago?
The average bus travel time from Appleton to Chicago is 4h 30m, covering a distance of 290 km. The quickest bus can get you there in 4h 30m and is operated by FlixBus.
Which bus companies service the Appleton to Chicago route?
What are the earliest and latest departure times for the bus from Appleton to Chicago?
The earliest bus departs from Appleton to Chicago at 9:30am. And the latest bus departs at 9:30am.
What are the CO₂ emissions for the bus trip from Appleton to Chicago?
A bus trip from Appleton to Chicago generates an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Appleton to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which bus company has the best Wi-Fi from Appleton to Chicago?
Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from Appleton to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Appleton to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Appleton to Chicago was searched and found on Dec 1, 2025 with a price of $51To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Appleton to Chicago, as early as possible.
You can expect to pay from $51 to $98 for a bus ticket from Appleton to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $51 which is on 2025-12-01.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
