Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Appleton | Downtown Greyhound Station | CheapestFastest | |||||
 | Appleton | Chicago (Union Station), IL | No tags | |||||
| Appleton | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Last Thursday at 10:31 PM CST.
Get from Appleton to Chicago
The journey takes about 4 hours 30 minutes, and with fares starting at just R 609, it presents an excellent value for a comfortable ride.
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Frequently asked questions about travelling from Appleton to Chicago by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Appleton to Chicago?
The cheapest bus tickets from Appleton to Chicago start at R 609. The average price for this route is around R 799. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Appleton to Chicago?
The average bus journey time from Appleton to Chicago is 4h 30m, covering a distance of 273 km. The fastest bus gets you there in 4h 30m and is operated by FlixBus.
Which bus companies service the Appleton to Chicago route?
What is the earliest and latest departure time for the bus from Appleton to Chicago?
The earliest bus departs from Appleton to Chicago at 09:30. And the latest bus departs at 09:30.
What are the CO₂ emissions for the bus trip from Appleton to Chicago?
A bus trip from Appleton to Chicago produces an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Appleton to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5627 reviews.
Which bus company has the best Wi-Fi from Appleton to Chicago?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company offers the most punctual service from Appleton to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Appleton to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Appleton to Chicago was searched and found on 12 Dec 2025 with a price of R 519To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Appleton to Chicago as early as possible.
You can expect to pay from R 519 to R 1 177 for a bus ticket from Appleton to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 554, which is on 2025-12-15.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
