Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Wilmington Bus Station | Wytheville Bus Station | No tags | ||||
| Bus | Wilmington Bus Station | Wytheville Bus Station | No tags | ||||
| Bus | Wilmington Bus Station | Wytheville Bus Station | No tags | ||||
| Bus | Wilmington Bus Station | Wytheville Bus Station | No tags | ||||
| Bus | Wilmington Bus Station | Wytheville Bus Station | No tags |
Get from Wilmington to Wytheville
The journey takes about 16 hours 35 minutes and with fares starting at just $59, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Wilmington, DE to Wytheville by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wilmington, DE to Wytheville was searched and found on Nov 11, 2025 with a price of $92To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Wytheville, as early as possible.
Top traveled bus routes
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Popular Buses Connecting Wilmington
Buses Leaving from Wilmington
- Bus from Wilmington to Wilmington
- Bus Wilmington - Myrtle Beach
- Wilmington - Charleston
- Bus from Wilmington to Philadelphia
- Bus Wilmington - Charleston
- Wilmington - Orlando
- Bus from Wilmington to New York City
- Bus Wilmington - Dover
- Wilmington - Baltimore
- Bus from Wilmington to Washington
- Bus Wilmington - Newark
- Wilmington - Smyrna
- Bus from Wilmington to Reading
- Bus Wilmington - Boston
- Wilmington - Atlanta
Buses Going to Wilmington
- Bus from Wilmington to Wilmington
- Bus Corning - Wilmington
- Atlanta - Wilmington
- Bus from Chicago to Wilmington
- Bus Pittsburgh - Wilmington
- New Castle - Wilmington
- Bus from New York City to Wilmington
- Bus Philadelphia - Wilmington
- Baltimore - Wilmington
- Bus from Newark to Wilmington
- Bus Washington - Wilmington
- Dover - Wilmington
- Bus from Boston to Wilmington
- Bus Norfolk - Wilmington
- Hartford - Wilmington
Popular Buses Connecting Wytheville
Buses Leaving from Wytheville
- Bus from Wytheville to Salem
- Bus Wytheville - Charlotte
- Wytheville - Raleigh
- Bus from Wytheville to Roanoke
- Bus Wytheville - Dallas
- Wytheville - New York City
- Bus from Wytheville to Los Angeles
- Bus Wytheville - Tampa
- Wytheville - Appleton
- Bus from Wytheville to Christiansburg
- Bus Wytheville - Wilmington
- Wytheville - Cincinnati
- Bus from Wytheville to Orlando
- Bus Wytheville - Austin
- Wytheville - Bristol
Buses Going to Wytheville
- Bus from Roanoke to Wytheville
- Bus Richmond - Wytheville
- San Antonio - Wytheville
- Bus from Upton to Wytheville
- Bus Lynchburg - Wytheville
- Nashville - Wytheville
- Bus from Cincinnati to Wytheville
- Bus New York City - Wytheville
- Flint - Wytheville
- Bus from Perry to Wytheville
- Bus Appleton - Wytheville
- Wilmington - Wytheville
- Bus from Charlotte to Wytheville
- Bus Akron - Wytheville
- Chicago - Wytheville
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
- Bus from Dallas to Austin
- Bus Miami - Tampa
- Austin - Houston
- Bus from Houston to San Antonio
- Bus Seattle - Leavenworth
- Houston - Austin
- Bus from San Antonio to Houston
- Bus Atlanta - Orlando
- Providence - New York City