Bus Tickets from Tampa to Greenville, SC

Previously seen trips

Next departures for Tampa to Greenville on October 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
Marion Transit Center North Platform
1116 Woodruff RdNo tags
Greyhound + FlixBus
University of South Florida
1116 Woodruff RdNo tags
FlixBus + Greyhound
Marion Transit Center North Platform
1116 Woodruff RdNo tags
Greyhound + FlixBus
University of South Florida
1116 Woodruff RdNo tags
FlixBus + Greyhound
Marion Transit Center North Platform
1116 Woodruff RdNo tags

Accepted payments

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  • China Union Pay
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Compare 2 ways to go from Tampa to Greenville.

Bus
Average Price$64 - $197Average Duration14h 40m
19kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$193 - $193Average Duration1d 12h
70kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Tampa to Greenville

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 14 hours 40 minutes and with fares starting at just $64, it presents an excellent value for a comfortable ride.

5bus per day
14h 40mAverage Duration
$64Cheapest ticket
19kgCO₂ emissions

Bus Tampa to Greenville, SC: Trip Overview

Average ticket price$109
Average bus trip duration14h 40m
Number of daily buses5
Earliest bus departure6:20am
Distance467 miles (752 km)
Latest bus departure10:35pm

Tampa to Greenville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Tampa to Greenville.

Bus service from Tampa to Greenville will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from Tampa, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Tampa - Greenville, SC

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/30
No data
10/01
No data
Today
No data
10/03
$105
10/04
No data
10/05
No data
10/06
No data
10/07
No data
busbud logoThe cheapest trip from Tampa to Greenville, SC was searched and found on Oct 3, 2025 with a price of $105

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Greenville, SC, as early as possible.

You can expect to pay from $105 to $105 for a bus ticket from Tampa to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $105 which is on 2025-10-03.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Tampa to Greenville but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Tampa to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Tampa to Greenville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tampa to Greenville.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Tampa to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Tampa by bus?

Bus from Greenville, SC to Tampa

You can also go to Greenville, SC by train

Train from Tampa to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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