How much is the bus ticket from Siena to Milano?

The cheapest bus tickets from Siena to Milano start from $12. The average price for this route is around $32. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Siena to Milano?

The average bus trip duration from Siena to Milano is 6h 30m, covering a distance of 184 miles (297 km). The quickest bus can get you there in 4h 30m and is operated by FlixBus .

Which bus companies service the Siena to Milano route?

Several major bus companies operate on this route with 33 buses available per day, including services from FlixBus , Itabus .

What is the earliest and latest departure time for the bus from Siena to Milano?

The earliest bus departs from Siena to Milano at 12:45am. And the latest bus departs at 11:55pm.

What are the CO₂ emissions for the bus trip from Siena to Milano?

A bus trip from Siena to Milano generates an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Siena to Milano?

According to Busbud customers, the highest-rated bus company on this route is Itabus , with an average rating of 3.8 out of 5 stars based on 945 reviews.

Which bus company has the best Wi-Fi from Siena to Milano?

Based on reviews on Busbud, the bus company Itabus has the best Wi-Fi rating with a score of 3.1.

Which bus company has the most timely service from Siena to Milano?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Siena to Milano?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Itabus , with a cleanliness rating of 4.3 out of 5 stars.

Bus Siena to Milano from $11 | Refundable Tickets

Next bus departures

Next departures for Siena to Milano on November 29
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:45pm	Siena Train Station	5h 34m	1:19am	Lampugnano bus station	Cheapest
Bus	7:45pm	Siena Train Station	5h	12:45am	Milan (San Donato M3)	Fastest
Bus	11:55pm	Siena Train Station	6h 55m	6:50am	Lampugnano	No tags
Bus	7:45pm	Siena Train Station	7h 25m	3:10am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	11:55pm	Siena Train Station	6h 55m	6:50am	Lampugnano	No tags

Next departures for Siena to Milano on November 30
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	Cheapest
Bus	12:45am	Siena Train Station	4h 30m	5:15am	Milan (San Donato M3)	Fastest
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus	12:45am	Siena Train Station	9h 15m	10:00am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags

Next departures for Siena to Milano on December 1
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	2:25pm	Siena Train Station	7h 20m	9:45pm	Lampugnano bus station	Cheapest
Bus	12:45am	Siena Train Station	4h 30m	5:15am	Milan (San Donato M3)	Fastest
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus	12:45am	Siena Train Station	9h 15m	10:00am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags

Next departures for Siena to Milano on December 2
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	3:05pm	Siena Train Station	6h 35m	9:40pm	Lampugnano bus station	Cheapest
Bus	12:45am	Siena Train Station	4h 30m	5:15am	Milan (San Donato M3)	Fastest
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus	12:45am	Siena Train Station	9h 15m	10:00am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags

Next departures for Siena to Milano on December 3
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	6:35pm	Siena Train Station	6h	12:35am	Lampugnano	Cheapest
Bus	12:45am	Siena Train Station	4h 30m	5:15am	Milan (San Donato M3)	Fastest
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus	12:45am	Siena Train Station	9h 15m	10:00am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags

Next departures for Siena to Milano on December 4
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	6:35pm	Siena Train Station	6h	12:35am	Lampugnano	Cheapest
Bus	12:45am	Siena Train Station	4h 30m	5:15am	Milan (San Donato M3)	Fastest
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus	12:45am	Siena Train Station	9h 15m	10:00am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags

Next departures for Siena to Milano on December 5
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	2:25pm	Siena Train Station	7h 20m	9:45pm	Lampugnano bus station	Cheapest
Bus	12:45am	Siena Train Station	4h 30m	5:15am	Milan (San Donato M3)	Fastest
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus	12:45am	Siena Train Station	9h 15m	10:00am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags

Next departures for Siena to Milano on December 6
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	2:25pm	Siena Train Station	7h 20m	9:45pm	Lampugnano bus station	Cheapest
Bus	12:45am	Siena Train Station	4h 30m	5:15am	Milan (San Donato M3)	Fastest
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus	12:45am	Siena Train Station	9h 15m	10:00am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags

Last refresh of the prices: Today at 4:44 PM CET.

Compare 2 ways to go from Siena to Milano

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as the good way to reach Milano. The journey takes about 3 hours 40 minutes and with fares starting at just $15, it presents an excellent value for a comfortable ride.

8carpool per day

3h 40mAverage Duration

182 milesDistance

12kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$12 - $167	Average Duration6h 30m	CO₂ emissions 7kg CO₂e
Carpool	Average Price$15 - $91	Average Duration3h 40m	CO₂ emissions 12kg CO₂e

Where are the popular stops in Siena and Milano?

Stops in Siena

A
Piazza Gramsci
Piazza Antonio Gramsci, 53100 Siena SI, Italy
Visit page
B
Via Sallustio Bandini, 21
Via Sallustio Bandini, 21, 53100 Siena SI, Italy
C
Via Giuseppe Mazzini, 58
Via Giuseppe Mazzini, 58, 53100 Siena SI, Italy
D
Via Riccardo Lombardi, 42
Via Riccardo Lombardi, 42, 53100 Siena SI, Italy
E
Torre Fiorentina
Torre Fiorentina, 53100 Siena SI, Italy
F
Siena Zona Industriale
Siena FS, 53100 Siena SI, Italy

Stops in Milano

A
Lampugnano
Via Giulio Natta, 228, 20151 Milano, Italy
Visit page
B
Piazza I Maggio, 1
Piazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
Visit page
C
Linate Airport
Visit page
D
Malpensa Airport
Visit page
E
Milan San Donato Bus Station
Via Giuseppe Impastato, 27, 20138 Milano, Italy
Visit page
F
Molino Dorino
Molino Dorino, 20151 Milano, Italy

Compare bus companies

FlixBus

3.5/511,473 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Itabus

4/5947 reviews

Staff4.3

Timeliness3

Cleanliness4.3

Wifi3.1

IT bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about traveling from Siena to Milano by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Siena to Milano?
The cheapest bus tickets from Siena to Milano start from $12. The average price for this route is around $32. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Siena to Milano?
The average bus trip duration from Siena to Milano is 6h 30m, covering a distance of 184 miles (297 km). The quickest bus can get you there in 4h 30m and is operated by FlixBus.
Which bus companies service the Siena to Milano route?
Several major bus companies operate on this route with 33 buses available per day, including services from FlixBus, Itabus.
What is the earliest and latest departure time for the bus from Siena to Milano?
The earliest bus departs from Siena to Milano at 12:45am. And the latest bus departs at 11:55pm.
What are the CO₂ emissions for the bus trip from Siena to Milano?
A bus trip from Siena to Milano generates an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Siena to Milano?
According to Busbud customers, the highest-rated bus company on this route is Itabus, with an average rating of 3.8 out of 5 stars based on 945 reviews.
Which bus company has the best Wi-Fi from Siena to Milano?
Based on reviews on Busbud, the bus company Itabus has the best Wi-Fi rating with a score of 3.1.
Which bus company has the most timely service from Siena to Milano?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Siena to Milano?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Itabus, with a cleanliness rating of 4.3 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/27

$15

11/28

$22

Today

$18

11/30

$28

12/01

$19

12/02

$14

12/03

$11

12/04

$11

The cheapest trip from Siena to Milano was searched and found on Dec 3, 2025 with a price of $11

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Siena to Milano, as early as possible.

You can expect to pay from $11 to $116 for a bus ticket from Siena to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $11 which is on 2025-12-03.

Usually Itabus, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.