Bus Tickets from San Francisco, US to Mesa

Next departures

Next departures for San Francisco to Mesa on October 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
San Francisco Bus Station
Mesa Bus StopCheapest
FlixBus + Greyhound Lines, Inc.
409 Townsend St, SF
Mesa Bus StopFastest
FlixBus + Greyhound Lines, Inc.
409 Townsend St, SF
Mesa Bus StopNo tags
Greyhound Lines, Inc.
San Francisco Bus Station
Mesa Bus StopNo tags
FlixBus + Greyhound Lines, Inc.
409 Townsend St, SF
Mesa Bus StopNo tags

Last refresh of the prices: Last Sunday at 9:29 AM PDT.

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Bus San Francisco, US to Mesa: Trip Overview

Average ticket price$86
Average bus trip duration19h 30m
Number of daily buses5
Earliest bus departure6:30am
Distance665 miles (1071 km)
Latest bus departure11:25pm

San Francisco to Mesa Bus

With Busbud, comparing and booking tickets for a bus from San Francisco to Mesa is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Francisco to Mesa.

Whether it is cheap bus tickets or more luxurious buses going to Mesa from San Francisco, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip San Francisco, US - Mesa

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/28
No data
09/29
$98
Today
No data
10/01
No data
10/02
No data
10/03
No data
10/04
$58
10/05
$77
busbud logoThe cheapest trip from San Francisco, US to Mesa was searched and found on Oct 4, 2025 with a price of $58

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to Mesa, as early as possible.

You can expect to pay from $58 to $142 for a bus ticket from San Francisco, US to Mesa based on the last 2 days. You can expect to find the cheapest price for the trip at $58 which is on 2025-10-04.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Francisco to Mesa.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Francisco to Mesa.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Francisco to Mesa.

Make a music playlist for your bus ride from San Francisco to Mesa, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to San Francisco, US by bus?

Bus from Mesa to San Francisco, US

Why choose Busbud?

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