Bus from San Diego, CA, US to San Antonio, US: Tickets & Schedules
Next bus departures
Next departures for San Diego to San Antonio on December 6
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + Valley Transit
Bus
Greyhound Bus Stop
San Antonio Bus Station
CheapestFastest
Next departures for San Diego to San Antonio on December 7
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
San Diego (Old Town-FlixBus)
San Antonio Bus Station
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
UCSD Health La Jolla Station
San Antonio Bus Station
Fastest
FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
San Diego (Old Town-FlixBus)
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
San Diego (Old Town-FlixBus)
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Greyhound Bus Stop
San Antonio Bus Station
No tags
Next departures for San Diego to San Antonio on December 8
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
San Diego (Old Town-FlixBus)
San Antonio Bus Station
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
UCSD Health La Jolla Station
San Antonio Bus Station
Fastest
FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
San Diego (Old Town-FlixBus)
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
San Diego (Old Town-FlixBus)
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Greyhound Bus Stop
San Antonio Bus Station
No tags
Next departures for San Diego to San Antonio on December 9
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
San Diego (Old Town-FlixBus)
San Antonio Bus Station
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
UCSD Health La Jolla Station
San Antonio Bus Station
Fastest
FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
San Diego (Old Town-FlixBus)
San Antonio Bus Station
No tags
Bus
Greyhound Bus Stop
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Valley Transit
Bus
Greyhound Bus Stop
San Antonio Bus Station
No tags
Next departures for San Diego to San Antonio on December 11
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
UCSD Health La Jolla Station
San Antonio Bus Station
CheapestFastest
FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
San Diego (Old Town-FlixBus)
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
San Diego (Old Town-FlixBus)
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Greyhound Bus Stop
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Valley Transit
Bus
Greyhound Bus Stop
San Antonio Bus Station
No tags
Last refresh of the prices: Last Wednesday at 12:31 AM PST.
Compare 2 ways to go from San Diego to San Antonio
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach San Antonio. The journey takes about 1 day, 10 hours 50 minutes and with fares starting at just $227, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from San Diego, CA, US to San Antonio, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from San Diego to San Antonio?
The cheapest bus tickets from San Diego to San Antonio start from $133. The average price for this route is around $216. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Diego to San Antonio?
The average bus trip duration from San Diego to San Antonio is 1d 13h, covering a distance of 1129 miles (1821 km). The quickest bus can get you there in 1d 8h and is operated by FlixBus.
Which bus companies service the San Diego to San Antonio route?
Several major bus companies operate on this route with 9 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from San Diego to San Antonio?
The earliest bus departs from San Diego to San Antonio at 6:45am. And the latest bus departs at 7:35pm.
What are the CO₂ emissions for the bus trip from San Diego to San Antonio?
A bus trip from San Diego to San Antonio generates an estimated 46 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from San Diego to San Antonio?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from San Diego to San Antonio?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from San Diego to San Antonio?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Diego to San Antonio?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
12/04
No data
12/05
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Today
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12/07
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12/08
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12/09
$178
12/10
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12/11
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The cheapest trip from San Diego, CA, US to San Antonio, US was searched and found on Dec 9, 2025 with a price of $178
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to San Antonio, US, as early as possible.
You can expect to pay from $178 to $178 for a bus ticket from San Diego, CA, US to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at $178 which is on 2025-12-09.
What's the cheapest way to go from San Diego, CA, US to San Antonio, US?
The bus is the cheapest travel choice for this destination
The cheapest trip from San Diego, CA, US to San Antonio, US was searched and found on Dec 9, 2025 with a price of $178
The bus is the cheapest travel choice for this destination
