Bus Tickets from San Diego, CA, US to San Antonio, US

Previously seen trips

Next departures for San Diego to San Antonio on September 24
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
UCSD Health La Jolla Station
San Antonio Bus StationNo tags
Greyhound + FlixBus
San Diego (Old Town-FlixBus)
San Antonio Bus StationNo tags
FlixBus + Greyhound
UCSD Health La Jolla Station
San Antonio Bus StationNo tags
Greyhound
Greyhound Bus Stop
San Antonio Bus StationNo tags
Greyhound + Valley Transit
Greyhound Bus Stop
San Antonio Bus StationNo tags

Accepted payments

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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from San Diego to San Antonio

Bus
Average PriceUS$105 - US$317Average Duration1d 13h
45kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$159 - US$299Average Duration1d 10h
165kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from San Diego to San Antonio

Among the sustainable travel choices, the train stands out as a good way to reach San Antonio. The journey takes about 1 day, 10 hours 50 minutes, and with fares starting at just US$159, it presents an excellent value for a comfortable ride.

2train per day
1d 10hAverage Duration
US$159Cheapest ticket
165kgCO₂ emissions

Bus San Diego, CA, US to San Antonio, US: Trip Overview

Average Ticket PriceUS$144
Average Bus Trip Duration1d 13h
Number of daily buses9
Earliest bus departure6:45am
Distance1817 km
Latest bus departure7:35pm

San Diego to San Antonio Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Diego to San Antonio.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Diego to San Antonio.

Whether it is cheap bus tickets or more luxurious buses going to San Antonio from San Diego, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip San Diego, CA, US - San Antonio, US

  1. What is the distance between San Diego and San Antonio?

    The distance between San Diego and San Antonio is around 1815 km (1125 miles).

  2. What are the departure and arrival locations for buses traveling from San Diego to San Antonio?

    Buses traveling this route start their trip at Mission Valley Sheraton, in San Diego, and end it at San Antonio Bus Station, in San Antonio.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-22
US$118
09-23
US$137
Today
US$121
09-25
No data
09-26
No data
09-27
No data
09-28
US$130
09-29
No data
busbud logoThe cheapest trip from San Diego, CA, US to San Antonio, US was searched and found on Sep 22, 2025 with a price of US$118

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to San Antonio, US, as early as possible.

You can expect to pay from US$118 to US$137 for a bus ticket from San Diego, CA, US to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$130 which is on 2025-09-28.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Diego to San Antonio but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Diego to San Antonio.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Diego to San Antonio.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to San Antonio.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from San Diego, CA, US to San Antonio, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Diego, CA, US by bus?

Bus from San Antonio, US to San Diego, CA, US

You can also go to San Antonio, US by train

Train from San Diego, CA, US to San Antonio, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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