How much is the bus ticket from Pittsburgh to Winston-Salem?

The cheapest bus tickets from Pittsburgh to Winston-Salem start from $98. The average price for this route is around $145. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Pittsburgh to Winston-Salem?

The average bus trip duration from Pittsburgh to Winston-Salem is 18h 15m, covering a distance of 300 miles (484 km). The quickest bus can get you there in 13h 50m and is operated by Greyhound .

Which bus companies service the Pittsburgh to Winston-Salem route?

Several major bus companies operate on this route with 2 buses available per day.

What is the earliest and latest departure time for the bus from Pittsburgh to Winston-Salem?

The earliest bus departs from Pittsburgh to Winston-Salem at 1:30am. And the latest bus departs at 9:00pm.

What are the CO₂ emissions for the bus trip from Pittsburgh to Winston-Salem?

A bus trip from Pittsburgh to Winston-Salem generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Bus Pittsburgh to Winston-Salem from $90 | Refundable Tickets

Next bus departures

Next departures for Pittsburgh to Winston-Salem on February 4
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:30am	Pittsburgh Intermodal Station	22h 15m	6:45am	Winston Salem Greyhound Bus Station	Cheapest
Bus	1:30am	Pittsburgh Intermodal Station	13h 50m	3:20pm	Winston Salem Greyhound Bus Station	Fastest
Bus	8:30pm	Pittsburgh Intermodal Station	18h 15m	2:45pm	Winston Salem Greyhound Bus Station	No tags

Next departures for Pittsburgh to Winston-Salem on February 5
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:30pm	Pittsburgh Intermodal Station	18h 15m	2:45pm	Winston Salem Greyhound Bus Station	Cheapest
Bus	1:30am	Pittsburgh Intermodal Station	13h 50m	3:20pm	Winston Salem Greyhound Bus Station	Fastest
Bus	8:30am	Pittsburgh Intermodal Station	22h 15m	6:45am	Winston Salem Greyhound Bus Station	No tags

Last refresh of the prices: Last Sunday at 5:31 AM EST.

Get from Pittsburgh to Winston-Salem

This route is served by bus only

The journey takes about 18 hours 15 minutes and with fares starting at just $98, it presents an excellent value for a comfortable ride.

2bus per day

18h 15mAverage Duration

300 milesDistance

12kgCO₂ emissions

Where are the popular stops in Pittsburgh and Winston-Salem?

Stops in Pittsburgh

A
Intermodal Station
55 11th St, Pittsburgh, PA 15222, USA
Visit page
B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA

Stops in Winston-Salem

A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101
Visit page
B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA
C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA
D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)

Compare bus companies

Greyhound

3.5/587,519 reviews

Staff3.6

Timeliness2.9

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Pittsburgh to Winston-Salem by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Pittsburgh to Winston-Salem?
The cheapest bus tickets from Pittsburgh to Winston-Salem start from $98. The average price for this route is around $145. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Pittsburgh to Winston-Salem?
The average bus trip duration from Pittsburgh to Winston-Salem is 18h 15m, covering a distance of 300 miles (484 km). The quickest bus can get you there in 13h 50m and is operated by Greyhound.
Which bus companies service the Pittsburgh to Winston-Salem route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Pittsburgh to Winston-Salem?
The earliest bus departs from Pittsburgh to Winston-Salem at 1:30am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Pittsburgh to Winston-Salem?
A bus trip from Pittsburgh to Winston-Salem generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

02/01

No data

02/02

No data

Today

No data

02/04

$137

02/05

$90

02/06

No data

02/07

No data

02/08

No data

The cheapest trip from Pittsburgh to Winston-Salem was searched and found on Feb 5, 2026 with a price of $90

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Winston-Salem, as early as possible.

You can expect to pay from $90 to $142 for a bus ticket from Pittsburgh to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $90 which is on 2026-02-05.