Bus Tickets from Philadelphia, PA to Winston-Salem

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TodayAug 8
from $150
TomorrowAug 9
from $122
SunAug 10
MonAug 11
from $78
TueAug 12
from $76
WedAug 13
from $76
ThuAug 14
from $70
FriAug 15

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 9 at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: August 10 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 9 at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: August 9 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 9 at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: August 10 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 9 at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: August 9 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 9 at
    Departure city: Philadelphia
    Departure location: Schuylkill & Walnut
    Arrival time: August 10 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Philadelphia to Winston-Salem.

Bus
Average Price$70 - $208Average Duration16h 40m
15kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$107 - $200Average Duration11h 39m
56kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Philadelphia to Winston-Salem

Among the sustainable travel choices, the train stands out as the good way to reach Winston-Salem. The journey takes about 11 hours 39 minutes and with fares starting at just $107, it presents an excellent value for a comfortable ride.

2train per day
11h 39mAverage Duration
$107Cheapest ticket
56kgCO₂ emissions

Bus Philadelphia, PA to Winston-Salem: Trip Overview

Average ticket price$104
Average bus trip duration16h 40m
Number of daily buses16
Earliest bus departure12:50am
Distance384 miles (618 km)
Latest bus departure10:30pm

Philadelphia to Winston-Salem Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Philadelphia to Winston-Salem.

Bus service from Philadelphia to Winston-Salem will be provided by the most trusted bus companies.

Discover how much the bus trip from Philadelphia to Winston-Salem will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Philadelphia, PA - Winston-Salem

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/06
$77
08/07
$82
Today
$142
08/09
$114
08/10
No data
08/11
$70
08/12
$68
08/13
$68
busbud logoThe cheapest trip from Philadelphia, PA to Winston-Salem was searched and found on Aug 12, 2025 with a price of $68

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Winston-Salem, as early as possible.

You can expect to pay from $68 to $189 for a bus ticket from Philadelphia, PA to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $68 which is on 2025-08-12.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Philadelphia to Winston-Salem but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Philadelphia to Winston-Salem, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Philadelphia to Winston-Salem will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Philadelphia to Winston-Salem, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

What's the cheapest way to go from Philadelphia, PA to Winston-Salem?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Philadelphia, PA by bus?

Bus from Philadelphia, PA to Winston-Salem

You can also go to Winston-Salem by train

Train from Philadelphia, PA to Winston-Salem

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