Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 199 Spring Garden St. | Winston Salem Greyhound Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Philadelphia, 199 Spring Garden St | Winston Salem Greyhound Bus Station | Fastest | ||||
| Bus | 199 Spring Garden St. | Winston Salem Greyhound Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Philadelphia, 199 Spring Garden St | Winston Salem Greyhound Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Philadelphia, 199 Spring Garden St | Winston Salem Greyhound Bus Station | No tags |
Last refresh of the prices: Today at 5:48 AM EST.
Get from Philadelphia to Winston-Salem
The journey takes about 16 hours 50 minutes, and with fares starting at just $96, it presents an excellent value for a comfortable ride.
Where are the popular stops in Philadelphia and Winston-Salem?
Stops in Philadelphia
- BOff of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
- C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA - D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA - E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA - F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
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Frequently asked questions about travelling from Philadelphia, PA to Winston-Salem by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Philadelphia to Winston-Salem?
The cheapest bus tickets from Philadelphia to Winston-Salem start from $96. The average price for this route is around $173. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Philadelphia to Winston-Salem?
The average bus travel time from Philadelphia to Winston-Salem is 16h 50m, covering a distance of 620 km. The quickest bus can get you there in 12h 20m and is operated by FlixBus.
Which bus companies service the Philadelphia to Winston-Salem route?
What are the earliest and latest departure times for the bus from Philadelphia to Winston-Salem?
The earliest bus departs from Philadelphia to Winston-Salem at 2:00am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Philadelphia to Winston-Salem?
A bus trip from Philadelphia to Winston-Salem generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Philadelphia to Winston-Salem?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Philadelphia to Winston-Salem?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Philadelphia to Winston-Salem?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Philadelphia to Winston-Salem?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Philadelphia, PA to Winston-Salem was searched and found on Dec 8, 2025 with a price of $86To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Winston-Salem, as early as possible.
You can expect to pay from $86 to $159 for a bus ticket from Philadelphia, PA to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $113 which is on 2025-12-09.
