Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Perugia-Autostazione Piazza Partigiani | Isernia | No tags | ||||
| Bus | Perugia-Autostazione Piazza Partigiani | Isernia | No tags | ||||
| Bus | Perugia (Stazione FS - Fontivegge) | Isernia | No tags | ||||
| Bus | Perugia-Autostazione Piazza Partigiani | Isernia | No tags | ||||
| Bus | Perugia-Autostazione Piazza Partigiani | Isernia | No tags |
Get from Perugia to Isernia
The journey takes about 12 hours 9 minutes and with fares starting at just $29, it presents an excellent value for a comfortable ride.
Where are the popular stops in Perugia and Isernia?
Stops in Perugia
- AViale Giovanni Perari, 06121 Perugia, Italy
- B
Perugia (P. Partigiani) fermata dell'autobus
Piazza Partigiani, 18, 06121 Perugia, Italy - C
Perugia Stazione
Str. di Prepo, 2, 06129 Perugia, Italy
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Perugia to Isernia by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Perugia to Isernia?
The cheapest bus tickets from Perugia to Isernia start from $29. The average price for this route is around $32. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Perugia to Isernia?
The average bus trip duration from Perugia to Isernia is 12h 9m, covering a distance of 141 miles (227 km). The quickest bus can get you there in 10h and is operated by FlixBus.
Which bus companies service the Perugia to Isernia route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Perugia to Isernia?
The earliest bus departs from Perugia to Isernia at 2:05am. And the latest bus departs at 7:00am.
What are the CO₂ emissions for the bus trip from Perugia to Isernia?
A bus trip from Perugia to Isernia generates an estimated 6 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Perugia to Isernia was searched and found on Mar 20, 2026 with a price of $26To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Perugia to Isernia, as early as possible.
You can expect to pay from $26 to $30 for a bus ticket from Perugia to Isernia based on the last 2 days. You can expect to find the cheapest price for the trip at $26 which is on 2026-03-20.
