Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Perugia-Autostazione Piazza Partigiani | Isernia | Cheapest | ||||
| Bus | Perugia (Stazione FS - Fontivegge) | Isernia | Fastest | ||||
| Bus | Perugia-Autostazione Piazza Partigiani | Isernia | No tags | ||||
| Bus | Perugia-Autostazione Piazza Partigiani | Isernia | No tags | ||||
| Bus | Perugia (Stazione FS - Fontivegge) | Isernia | No tags |
Last refresh of the prices: Today at 8:27 AM CET.
Get from Perugia to Isernia
The journey takes about 9 hours 59 minutes, and with fares starting at just $86, it presents an excellent value for a comfortable ride.
Where are the popular stops in Perugia and Isernia?
Stops in Perugia
- AViale Giovanni Perari, 06121 Perugia, Italy
- B
Perugia (P. Partigiani) fermata dell'autobus
Piazza Partigiani, 18, 06121 Perugia, Italy - C
Perugia Stazione
Str. di Prepo, 2, 06129 Perugia, Italy
Compare bus companies
Based on 11626 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $86
Frequently asked questions about travelling from Perugia to Isernia by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Perugia to Isernia?
The cheapest bus tickets from Perugia to Isernia start from $86. The average price for this route is around $86. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Perugia to Isernia?
The average bus travel time from Perugia to Isernia is 9h 59m, covering a distance of 227 km. The quickest bus can get you there in 9h 49m and is operated by FlixBus.
Which bus companies service the Perugia to Isernia route?
Several major bus companies operate on this route with 4 buses available per day.
What are the earliest and latest departure times for the bus from Perugia to Isernia?
The earliest bus departs from Perugia to Isernia at 1:25am. And the latest bus departs at 3:40am.
What are the CO₂ emissions for the bus trip from Perugia to Isernia?
A bus trip from Perugia to Isernia generates an estimated 6 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Perugia to Isernia was searched and found on Dec 20, 2025 with a price of $97To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Perugia to Isernia, as early as possible.
You can expect to pay from $97 to $124 for a bus ticket from Perugia to Isernia based on the last 2 days. You can expect to find the cheapest price for the trip at $97 which is on 2025-12-20.
