Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gare routière de Mulhouse | Lyon - Perrache Bus Station | CheapestFastest | ||||
 | Bus | Mulhouse | Aéroport LYS | No tags | ||||
| Bus | Mulhouse | Perrache | No tags | ||||
| Bus | Mulhouse | Perrache | No tags |
Last refresh of the prices: Today at 6:51 PM CET.
Compare 2 ways to go from Mulhouse to Lyon
Among the sustainable travel choices, the carpool stands out as the good way to reach Lyon. The journey takes about 3 hours 50 minutes and with fares starting at just $22, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$20 - $77 | Average Duration6h | 7kg CO₂e | ||
Carpool | Average Price$22 - $68 | Average Duration3h 50m | 12kg CO₂e |
Where are the popular stops in Mulhouse and Lyon?
Stops in Mulhouse
- A14 Avenue du Général Leclerc, 68100 Mulhouse , France
- B
Arrêt d'Autobus Mulhouse - Parking Bus Esso Napoleon
Rue Jean Monnet, 68390 Sausheim, France - C
Arrêt d'autobus Mulhouse
- D
Gare Routière de Mulhouse - Devant la gare SNCF
8 Avenue du Général Leclerc, 68100 Mulhouse, France - E
Arrêt d'autobus Bâle Aéroport
E25, 68300 Saint-Louis, France
Stops in Lyon
- BRue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
Compare bus companies
Frequently asked questions about traveling from Mulhouse to Lyon by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mulhouse to Lyon?
The cheapest bus tickets from Mulhouse to Lyon start from $20. The average price for this route is around $42. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mulhouse to Lyon?
The average bus trip duration from Mulhouse to Lyon is 6h, covering a distance of 182 miles (294 km). The quickest bus can get you there in 4h 25m and is operated by FlixBus.
Which bus companies service the Mulhouse to Lyon route?
Several major bus companies operate on this route with 3 buses available per day, including services from FlixBus, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Mulhouse to Lyon?
The earliest bus departs from Mulhouse to Lyon at 12:10am. And the latest bus departs at 11:54pm.
What are the CO₂ emissions for the bus trip from Mulhouse to Lyon?
A bus trip from Mulhouse to Lyon generates an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Mulhouse to Lyon?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11143 reviews.
Which bus company has the best Wi-Fi from Mulhouse to Lyon?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Mulhouse to Lyon?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Mulhouse to Lyon?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mulhouse to Lyon was searched and found on Dec 2, 2025 with a price of $23To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mulhouse to Lyon, as early as possible.
You can expect to pay from $23 to $60 for a bus ticket from Mulhouse to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $23 which is on 2025-12-02.
Usually BlaBlaCar Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
