Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Greyhound Station | Panama City Beach Station | No tags | ||||
| Bus | Greyhound Station | Panama City Beach Station | No tags | ||||
| Bus | Greyhound Station | Panama City Beach Station | No tags | ||||
| Bus | Greyhound Station | Panama City Beach Station | No tags | ||||
| Bus | Greyhound Station | Panama City Beach Station | No tags |
Get from Mobile to Panama City
The journey takes about 3 hours 40 minutes and with fares starting at just $30, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mobile and Panama City?
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Mobile to Panama City, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mobile to Panama City?
The cheapest bus tickets from Mobile to Panama City start from $30. The average price for this route is around $39. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mobile to Panama City?
The average bus trip duration from Mobile to Panama City is 3h 40m, covering a distance of 143 miles (230 km). The quickest bus can get you there in 3h 35m and is operated by Greyhound.
Which bus companies service the Mobile to Panama City route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Mobile to Panama City?
The earliest bus departs from Mobile to Panama City at 3:45am. And the latest bus departs at 8:45am.
What are the CO₂ emissions for the bus trip from Mobile to Panama City?
A bus trip from Mobile to Panama City generates an estimated 6 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mobile to Panama City, US was searched and found on Dec 5, 2025 with a price of $23To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mobile to Panama City, US, as early as possible.
You can expect to pay from $23 to $28 for a bus ticket from Mobile to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $23 which is on 2025-12-05.
