What is the distance between Lafayette and St. Louis?

The distance between the two cities is 590 miles (951 km).

What are the departure and arrival stations when taking the bus from Lafayette to St. Louis?

If you're headed to St. Louis from Lafayette, chances are that your bus will depart from TA Travel Center - Lafayette and arrive at Gateway Station. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

What are the best sights and things to do in St. Louis?

Once in St. Louis, you can start exploring the city and discover its surroundings. The top sights and things to do are St. Louis Cardinals, Saint Louis Zoo, Powell Symphony Hall, Old St. Louis County Courthouse and Ulysses S. Grant National Historic Site.

Bus Lafayette to St. Louis from $88 | Refundable Tickets

Next departures

Next departures for Lafayette to St. Louis on August 27
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	5:30pm	Lafayette Transit System	1d 3h	9:25pm	Gateway Station	Cheapest
	9:20pm	Lafayette Transit System	1d 1h	10:20pm	Saint Louis (Lambert Field)	Fastest
	9:20pm	Lafayette Transit System	1d 1h	10:50pm	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	12:50pm	TA Travel Center - Lafayette	1d 8h	9:25pm	Gateway Station	No tags
	9:20pm	Lafayette Transit System	1d 1h	10:20pm	Saint Louis (Lambert Field)	No tags

Next departures for Lafayette to St. Louis on August 30
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	10:10pm	Lafayette Transit System	1d	10:20pm	Saint Louis (Lambert Field)	Cheapest
	8:50pm	TA Travel Center - Lafayette	18h 55m	3:45pm	Gateway Station	Fastest
Greyhound Lines, Inc. + FlixBus	3:55am	Lafayette Transit System	1d 3h	7:15am	Gateway Station	No tags
	9:20am	Lafayette Transit System	1d 3h	12:55pm	Gateway Station	No tags
	8:50pm	TA Travel Center - Lafayette	18h 55m	3:45pm	Gateway Station	No tags

Next departures for Lafayette to St. Louis on September 2
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	8:30am	TA Travel Center - Lafayette	1d 4h	12:55pm	Gateway Station	Cheapest
	9:20pm	Lafayette Transit System	1d 1h	10:20pm	Saint Louis (Lambert Field)	Fastest
	9:20am	Lafayette Transit System	1d 3h	12:55pm	Gateway Station	No tags
Greyhound Lines, Inc. + FlixBus	5:30pm	Lafayette Transit System	1d 3h	9:25pm	Gateway Station	No tags
FlixBus + Greyhound Lines Mexico + Greyhound Lines, Inc.	3:25pm	TA Travel Center - Lafayette	1d 6h	10:20pm	Saint Louis (Lambert Field)	No tags

Bus Lafayette, LA to St. Louis: Trip Overview

Average ticket price$137

Average bus trip duration1d 3h

Number of daily buses9

Earliest bus departure1:30am

Distance587 miles (946 km)

Latest bus departure10:10pm

Compare bus companies

Greyhound

3.5/587,210 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/510,262 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

Lafayette to St. Louis Bus

Busbud helps you find a bus from Lafayette to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Lafayette to St. Louis.

Discover how much the bus trip from Lafayette to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in Lafayette and St. Louis?

Stops in Lafayette

A - TA Travel Center - Lafayette

B - Lafayette A and J Travel Bus Station

C - Lafayette Bus Stop

Stops in St. Louis

A - Gateway Station

Frequently asked questions for your trip Lafayette, LA - St. Louis

What is the distance between Lafayette and St. Louis?
What are the departure and arrival stations when taking the bus from Lafayette to St. Louis?
What are the best sights and things to do in St. Louis?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

08/25

$126

08/26

$150

Today

$134

08/28

No data

08/29

$118

08/30

$129

08/31

No data

09/01

No data

The cheapest trip from Lafayette, LA to St. Louis was searched and found on Aug 29, 2025 with a price of $118

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette, LA to St. Louis, as early as possible.

You can expect to pay from $118 to $242 for a bus ticket from Lafayette, LA to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $118 which is on 2025-08-29.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Lafayette and St. Louis!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Lafayette to St. Louis.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Lafayette to St. Louis will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Lafayette to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Lafayette, LA by bus?

Bus from St. Louis to Lafayette, LA

Top traveled bus routes

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The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Lafayette, LA to St. Louis

Next departures

Bus Lafayette, LA to St. Louis: Trip Overview

Compare bus companies

Lafayette to St. Louis Bus

Where are the popular stops in Lafayette and St. Louis?

Frequently asked questions for your trip Lafayette, LA - St. Louis

What is the distance between Lafayette and St. Louis?

What are the departure and arrival stations when taking the bus from Lafayette to St. Louis?

What are the best sights and things to do in St. Louis?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

Will you be returning to Lafayette, LA by bus?

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

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