How much is the bus ticket from St. Louis to Indianapolis?

The cheapest bus tickets from St. Louis to Indianapolis start from $40. The average price for this route is around $50. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from St. Louis to Indianapolis?

The average bus trip duration from St. Louis to Indianapolis is 4h 25m, covering a distance of 230 miles (371 km). The quickest bus can get you there in 4h 25m and is operated by Greyhound .

Which bus companies service the St. Louis to Indianapolis route?

Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from St. Louis to Indianapolis?

The earliest bus departs from St. Louis to Indianapolis at 2:00am. And the latest bus departs at 11:30pm.

What are the CO₂ emissions for the bus trip from St. Louis to Indianapolis?

A bus trip from St. Louis to Indianapolis generates an estimated 9 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from St. Louis to Indianapolis?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87387 reviews.

Which bus company has the best Wi-Fi from St. Louis to Indianapolis?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from St. Louis to Indianapolis?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from St. Louis to Indianapolis?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus St. Louis to Indianapolis from $32 | Refundable Tickets

Next bus departures

Next departures for St. Louis to Indianapolis on December 3
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:45am	Gateway Station	4h 45m	2:30pm	Indianapolis Bus Station	Cheapest
Bus	2:00am	Gateway Station	4h 25m	7:25am	Indianapolis Bus Station	Fastest
Bus	1:55pm	Gateway Station	4h 25m	7:20pm	Indianapolis Bus Station	No tags

Next departures for St. Louis to Indianapolis on December 4
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:45am	Gateway Station	4h 45m	2:30pm	Indianapolis Bus Station	Cheapest
Bus	2:00am	Gateway Station	4h 25m	7:25am	Indianapolis Bus Station	Fastest
Bus	1:55pm	Gateway Station	4h 25m	7:20pm	Indianapolis Bus Station	No tags

Next departures for St. Louis to Indianapolis on December 5
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:45am	Gateway Station	4h 45m	2:30pm	Indianapolis Bus Station	Cheapest
Bus	2:00am	Gateway Station	4h 25m	7:25am	Indianapolis Bus Station	Fastest
Bus	1:55pm	Gateway Station	4h 25m	7:20pm	Indianapolis Bus Station	No tags

Next departures for St. Louis to Indianapolis on December 6
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:45am	Gateway Station	4h 45m	2:30pm	Indianapolis Bus Station	Cheapest
Bus	2:00am	Gateway Station	4h 25m	7:25am	Indianapolis Bus Station	Fastest
Bus	1:55pm	Gateway Station	4h 25m	7:20pm	Indianapolis Bus Station	No tags

Next departures for St. Louis to Indianapolis on December 7
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	2:00am	Gateway Station	4h 25m	7:25am	Indianapolis Bus Station	CheapestFastest
Bus	8:45am	Gateway Station	4h 45m	2:30pm	Indianapolis Bus Station	No tags
Bus	1:55pm	Gateway Station	4h 25m	7:20pm	Indianapolis Bus Station	No tags

Last refresh of the prices: Today at 7:27 AM CST.

Compare 2 ways to go from St. Louis to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 4 hours 25 minutes and with fares starting at just $40, it presents an excellent value for a comfortable ride.

3bus per day

4h 25mAverage Duration

230 milesDistance

9kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$40 - $147	Average Duration4h 25m	CO₂ emissions 9kg CO₂e
Train	Average Price$70 - $598	Average Duration14h 39m	CO₂ emissions 34kg CO₂e

Where are the popular stops in St. Louis and Indianapolis?

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Compare bus companies

Greyhound

3.5/587,412 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound St. Louis Indianapolis recent customer reviews

My Journey to Indianapolis was quite interesting. I really like the bus driver he was very approachable. I appreciate that he got us to our destination in Indianapolis safely and early. I must say the bus was a old and I had to change seats several times due to water leaking on top of my head. Otherwise, I had no additional problems but that the bus needed to be upgraded. Please let the bus driver know that he was great and thank him for the chat. Sincerely, Courtney

Courtney M.

October 22, 2019

I hope my round trip back home is better. My bus left 5 1/2 hours later than expected on the ride over to Indianapolis. Plus there were mo clear directions to the busport in St Louis. Even the terminal crew could not tell us where to catch the bus. The address given may have been the address in general for the whole airport. Signage unclear and we drove in circles looking for a busport which was actually across the hwy from the airport.

Linda T.

September 8, 2019

I was under the impression that we would get to our destination around 7:30 but didn’t make it until around 9. I understand there was a time change but I feel like the ticket should have reflected that time change if that was the case.

Tresden M.

October 20, 2018

FlixBus

3.5/511,492 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from St. Louis to Indianapolis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from St. Louis to Indianapolis?
The cheapest bus tickets from St. Louis to Indianapolis start from $40. The average price for this route is around $50. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to Indianapolis?
The average bus trip duration from St. Louis to Indianapolis is 4h 25m, covering a distance of 230 miles (371 km). The quickest bus can get you there in 4h 25m and is operated by Greyhound.
Which bus companies service the St. Louis to Indianapolis route?
Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from St. Louis to Indianapolis?
The earliest bus departs from St. Louis to Indianapolis at 2:00am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from St. Louis to Indianapolis?
A bus trip from St. Louis to Indianapolis generates an estimated 9 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from St. Louis to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from St. Louis to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from St. Louis to Indianapolis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/29

$81

11/30

$100

Today

$56

12/02

$53

12/03

$36

12/04

$32

12/05

$35

12/06

$35

The cheapest trip from St. Louis to Indianapolis was searched and found on Dec 4, 2025 with a price of $32

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Indianapolis, as early as possible.

You can expect to pay from $32 to $149 for a bus ticket from St. Louis to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $32 which is on 2025-12-04.