How much does a bus ticket from St. Louis to Indianapolis cost?

The bus ticket price from St. Louis to Indianapolis starts at US$40. The best way to find cheap bus tickets from St. Louis to Indianapolis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the bus ride from St. Louis to Indianapolis?

The average travel time between St. Louis and Indianapolis is around 4h 25m, although the fastest bus will take about 4h 25m. This is the time it takes to travel the 371 km that separates the two cities.

How many daily bus connections are there between St. Louis and Indianapolis?

The number of buses from St. Louis to Indianapolis can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from St. Louis to Indianapolis by comparing and selecting the bus that fits your travel style and budget on Busbud.

Which bus companies travel from St. Louis to Indianapolis?

When taking the bus from St. Louis to Indianapolis, you can travel comfortably and safely with Greyhound, FlixBus.

Bus St. Louis to Indianapolis from US$34 | Refundable Tickets

Next departures

Next departures from St. Louis to Indianapolis on 1 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
		08:45	Gateway Station	4h 45m	14:30	Indianapolis Bus Station	Cheapest
		13:55	Gateway Station	4h 25m	19:20	Indianapolis Bus Station	Fastest

Next departures from St. Louis to Indianapolis on 2 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
08:45	Gateway Station	4h 45m	14:30	Indianapolis Bus Station	Cheapest
02:00	Gateway Station	4h 25m	07:25	Indianapolis Bus Station	Fastest
13:55	Gateway Station	4h 25m	19:20	Indianapolis Bus Station	No tags

Next departures from St. Louis to Indianapolis on 4 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
08:45	Gateway Station	4h 45m	14:30	Indianapolis Bus Station	Cheapest
02:00	Gateway Station	4h 25m	07:25	Indianapolis Bus Station	Fastest
13:55	Gateway Station	4h 25m	19:20	Indianapolis Bus Station	No tags

Next departures from St. Louis to Indianapolis on 6 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
08:45	Gateway Station	4h 45m	14:30	Indianapolis Bus Station	Cheapest
02:00	Gateway Station	4h 25m	07:25	Indianapolis Bus Station	Fastest
13:55	Gateway Station	4h 25m	19:20	Indianapolis Bus Station	No tags

Next departures from St. Louis to Indianapolis on 8 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
13:55	Gateway Station	4h 25m	19:20	Indianapolis Bus Station	Cheapest
02:00	Gateway Station	4h 25m	07:25	Indianapolis Bus Station	Fastest
08:45	Gateway Station	4h 45m	14:30	Indianapolis Bus Station	No tags

Last refresh of the prices: Yesterday at 8:54 PM CDT.

Compare 2 ways to travel from St. Louis to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 4 hours 25 minutes and with fares starting at just US$40, it presents an excellent value for a comfortable ride.

3bus per day

4h 25mAverage duration

371 kmDistance

9kgCO₂ emissions

	Average price	Average duration	CO₂ emissions
Bus	Average priceUS$40 - US$142	Average duration4h 25m	CO₂ emissions 9kg CO₂e
Train	Average priceUS$70 - US$146	Average duration14h 39m	CO₂ emissions 34kg CO₂e

Bus St. Louis to Indianapolis: Trip Overview

Average ticket priceUS$47

Average bus trip duration4h 25m

Number of daily buses3

Earliest bus departure02:00

Distance371 km

Latest bus departure23:30

Compare bus companies

Greyhound

3.5/587 345 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

Based on 87345 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at US$40

Greyhound St. Louis Indianapolis recent customer reviews

My Journey to Indianapolis was quite interesting. I really like the bus driver he was very approachable. I appreciate that he got us to our destination in Indianapolis safely and early. I must say the bus was a old and I had to change seats several times due to water leaking on top of my head. Otherwise, I had no additional problems but that the bus needed to be upgraded. Please let the bus driver know that he was great and thank him for the chat. Sincerely, Courtney

Courtney M.

22 October 2019

I hope my round trip back home is better. My bus left 5 1/2 hours later than expected on the ride over to Indianapolis. Plus there were mo clear directions to the busport in St Louis. Even the terminal crew could not tell us where to catch the bus. The address given may have been the address in general for the whole airport. Signage unclear and we drove in circles looking for a busport which was actually across the hwy from the airport.

Linda T.

8 September 2019

I was under the impression that we would get to our destination around 7:30 but didn’t make it until around 9. I understand there was a time change but I feel like the ticket should have reflected that time change if that was the case.

Tresden M.

20 October 2018

FlixBus

3.5/511 139 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, Sindbad, Infobus, Gontijo, Rider Express

St. Louis to Indianapolis Bus

With Busbud, comparing and booking tickets for a bus from St. Louis to Indianapolis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from St. Louis to Indianapolis will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from St. Louis to Indianapolis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Where are the popular stops in St. Louis and Indianapolis?

Stops in St. Louis

A - Gateway Station

Stops in Indianapolis

A - Greyhound Amtrak Station

Frequently asked questions on the trip St. Louis - Indianapolis

How much does a bus ticket from St. Louis to Indianapolis cost?
The bus ticket price from St. Louis to Indianapolis starts at US$40. The best way to find cheap bus tickets from St. Louis to Indianapolis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from St. Louis to Indianapolis?
The average travel time between St. Louis and Indianapolis is around 4h 25m, although the fastest bus will take about 4h 25m. This is the time it takes to travel the 371 km that separates the two cities.
How many daily bus connections are there between St. Louis and Indianapolis?
The number of buses from St. Louis to Indianapolis can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from St. Louis to Indianapolis by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from St. Louis to Indianapolis?
When taking the bus from St. Louis to Indianapolis, you can travel comfortably and safely with Greyhound, FlixBus.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

30/10

US$117

31/10

US$124

Today

US$64

02/11

US$50

03/11

US$38

04/11

US$40

05/11

US$36

06/11

US$40

The cheapest trip from St. Louis to Indianapolis was searched and found on 05 Nov 2025 with a price of US$36

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Indianapolis as early as possible.

You can expect to pay from US$36 to US$129 for a bus ticket from St. Louis to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at US$36, which is on 2025-11-05.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from St. Louis to Indianapolis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from St. Louis to Indianapolis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St. Louis to Indianapolis that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from St. Louis to Indianapolis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from St. Louis to Indianapolis?

The bus is the cheapest travel choice for this destination

Vehicle type	Travel time	Avg price	Daily departures
Vehicle typeBus	Travel time4h 25m	Avg priceUS$47	Daily departures3
Vehicle typeTrain	Travel time14h 39m	Avg priceUS$86	Daily departures1

Will you be returning to St. Louis by bus?

Bus from Indianapolis to St. Louis

You can also go to Indianapolis by train

Train from St. Louis to Indianapolis

Top travelled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Find coaches from St. Louis to Indianapolis