Bus Tickets from Iquique to Santiago, CL

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TodayAug 11
TomorrowAug 12
from $39
WedAug 13
from $39
ThuAug 14
from $31
FriAug 15
from $31
SatAug 16
from $39
SunAug 17
from $52
MonAug 18
from $31

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 12 at
    Departure city: Iquique
    Departure location: Terminal Rodoviario De Iquique, Calle Patricio Lynch #50
    Arrival time: August 13 at
    Destination city: Santiago
    Destination location: Terminal de Buses San Borja - San Francisco de Borja
    Operated by: Cikbus ElitéCikbus Elité
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 12 at
    Departure city: Iquique
    Departure location: Terminal Rodoviario Iquique
    Arrival time: August 13 at
    Destination city: Santiago
    Destination location: San Borja
    Operated by: Pullman San AndrésPullman San Andrés
    Vehicle: BusDuration:
  • Departure time: August 12 at
    Departure city: Iquique
    Departure location: Terminal Rodoviario De Iquique, Calle Patricio Lynch #50
    Arrival time: August 13 at
    Destination city: Santiago
    Destination location: Terminal de Buses San Borja - San Francisco de Borja
    Operated by: Cikbus ElitéCikbus Elité
    Vehicle: BusDuration:
  • Departure time: August 12 at
    Departure city: Iquique
    Departure location: Terminal Rodoviario De Iquique, Calle Patricio Lynch #50
    Arrival time: August 13 at
    Destination city: Santiago
    Destination location: San Borja
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:
  • Departure time: August 12 at
    Departure city: Iquique
    Departure location: Terminal Rodoviario De Iquique, Calle Patricio Lynch #50
    Arrival time: August 13 at
    Destination city: Santiago
    Destination location: Terminal de Buses San Borja
    Operated by: AndimarAndimar
    Vehicle: BusDuration:

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Bus Iquique to Santiago, CL: Trip Overview

Average ticket price$59
Average bus trip duration1d
Number of daily buses22
Earliest bus departure12:30am
Distance914 miles (1474 km)
Latest bus departure11:59pm

Iquique to Santiago Bus

With Busbud, comparing and booking tickets for a bus from Iquique to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Iquique to Santiago from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Santiago from Iquique, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Iquique - Santiago, CL

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/09
$36
08/10
$36
Today
$36
08/12
$36
08/13
$36
08/14
$29
08/15
$29
08/16
$36
busbud logoThe cheapest trip from Iquique to Santiago, CL was searched and found on Aug 15, 2025 with a price of $29

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Iquique to Santiago, CL, as early as possible.

You can expect to pay from $29 to $67 for a bus ticket from Iquique to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $29 which is on 2025-08-15.

Usually PlussChile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Iquique to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Iquique to Santiago, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Iquique to Santiago.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Iquique to Santiago.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Iquique by bus?

Bus from Iquique to Santiago, CL

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