Bus from Gainesville, FL to Key West: Tickets & Schedules

Next bus departures

Next departures for Gainesville to Key West on November 29
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Rosa Parks Station
Key West Bus StationCheapest
Greyhound Lines, Inc.Bus
Gainesville Bus Stop
Key West Bus StationFastest
Greyhound Lines, Inc. + FlixBus
Bus
Gainesville Bus Stop
Key West Bus StationNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Rosa Parks Station
Key West Bus StationNo tags

Last refresh of the prices: Today at 8:08 AM EST.

Get from Gainesville to Key West

This route is served by bus only

The journey takes about 15 hours 25 minutes and with fares starting at just $62, it presents an excellent value for a comfortable ride.

4bus per day
15h 25mAverage Duration
358 milesDistance
14kgCO₂ emissions

Frequently asked questions about traveling from Gainesville, FL to Key West by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Gainesville to Key West?

    The cheapest bus tickets from Gainesville to Key West start from $62. The average price for this route is around $117. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Gainesville to Key West?

    The average bus trip duration from Gainesville to Key West is 15h 25m, covering a distance of 358 miles (577 km). The quickest bus can get you there in 14h 35m and is operated by FlixBus.

  3. Which bus companies service the Gainesville to Key West route?

    Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Gainesville to Key West?

    The earliest bus departs from Gainesville to Key West at 12:35am. And the latest bus departs at 10:40pm.

  5. What are the CO₂ emissions for the bus trip from Gainesville to Key West?

    A bus trip from Gainesville to Key West generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Gainesville to Key West?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.

  7. Which bus company has the best Wi-Fi from Gainesville to Key West?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Gainesville to Key West?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Gainesville to Key West?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/26
No data
11/27
No data
Today
No data
11/29
$123
11/30
$102
12/01
$115
12/02
$146
12/03
$88
busbud logoThe cheapest trip from Gainesville, FL to Key West was searched and found on Dec 3, 2025 with a price of $88

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Key West, as early as possible.

You can expect to pay from $88 to $146 for a bus ticket from Gainesville, FL to Key West based on the last 2 days. You can expect to find the cheapest price for the trip at $88 which is on 2025-12-03.

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