Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Orlando Bus Station | Key West Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | The Florida Mall | Key West Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Key West Bus Station | No tags |
Last refresh of the prices: Yesterday at 3:20 PM EST.
Get from Orlando to Key West
The journey takes about 10 hours and with fares starting at just $48, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and Key West?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Stops in Key West
- A908 Caroline St, Key West, FL 33040, USA
- B
EYW Airport
3535 Florida A1A, Key West, FL 33040, USA
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Frequently asked questions about traveling from Orlando to Key West by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Orlando to Key West?
The cheapest bus tickets from Orlando to Key West start from $48. The average price for this route is around $71. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Orlando to Key West?
The average bus trip duration from Orlando to Key West is 10h, covering a distance of 270 miles (435 km). The quickest bus can get you there in 10h 25m and is operated by FlixBus.
Which bus companies service the Orlando to Key West route?
What is the earliest and latest departure time for the bus from Orlando to Key West?
The earliest bus departs from Orlando to Key West at 1:15am. And the latest bus departs at 10:35pm.
What are the CO₂ emissions for the bus trip from Orlando to Key West?
A bus trip from Orlando to Key West generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Orlando to Key West?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Orlando to Key West?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Orlando to Key West?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Orlando to Key West?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Key West was searched and found on Nov 27, 2025 with a price of $75To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Key West, as early as possible.
You can expect to pay from $75 to $89 for a bus ticket from Orlando to Key West based on the last 2 days. You can expect to find the cheapest price for the trip at $89 which is on 2025-11-29.
