Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Rosa Parks Station | Key West Bus Station | Cheapest | ||||
 | Bus | Gainesville Bus Stop | Key West Bus Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Gainesville Bus Stop | Key West Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Rosa Parks Station | Key West Bus Station | No tags |
Last refresh of the prices: Yesterday at 8:08 AM EST.
Get from Gainesville to Key West
The journey takes about 15 hours 25 minutes, and with fares starting at just $89, it presents an excellent value for a comfortable ride.
Where are the popular stops in Gainesville and Key West?
Stops in Gainesville
- A700 SE 3rd St, Gainesville, FL 32601
- B3509 SW Williston Rd, Gainesville, FL 32608, USA
- C101 NE 23rd Ave, Gainesville, FL 32609
Stops in Key West
- A908 Caroline St, Key West, FL 33040, USA
- B
EYW Airport
3535 Florida A1A, Key West, FL 33040, USA
Compare bus companies
Frequently asked questions about travelling from Gainesville, FL to Key West by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Gainesville to Key West?
The cheapest bus tickets from Gainesville to Key West start from $89. The average price for this route is around $167. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Gainesville to Key West?
The average bus travel time from Gainesville to Key West is 15h 25m, covering a distance of 577 km. The quickest bus can get you there in 14h 35m and is operated by FlixBus.
Which bus companies service the Gainesville to Key West route?
What are the earliest and latest departure times for the bus from Gainesville to Key West?
The earliest bus departs from Gainesville to Key West at 12:35am. And the latest bus departs at 10:40pm.
What are the CO₂ emissions for the bus trip from Gainesville to Key West?
A bus trip from Gainesville to Key West generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Gainesville to Key West?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Gainesville to Key West?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Gainesville to Key West?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Gainesville to Key West?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Gainesville, FL to Key West was searched and found on Dec 3, 2025 with a price of $126To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Key West, as early as possible.
You can expect to pay from $126 to $210 for a bus ticket from Gainesville, FL to Key West based on the last 2 days. You can expect to find the cheapest price for the trip at $126 which is on 2025-12-03.
