Bus Tickets from Gainesville, FL to Chicago

Previously seen trips

Next departures for Gainesville to Chicago on November 15
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Bus
Rosa Parks Station
537-517 W. Jackson BlvdNo tags
FlixBus + Greyhound
Bus
Rosa Parks Station
Chicago 95Th & Dan RyanNo tags
FlixBus + Greyhound
Bus
Rosa Parks Station
Downtown Greyhound StationNo tags
FlixBus + Greyhound
Bus
Gainesville Bus Stop
Chicago 95Th & Dan RyanNo tags
FlixBus + Greyhound
Bus
Gainesville Bus Stop
537-517 W. Jackson BlvdNo tags

Get from Gainesville to Chicago

This route is served by bus only

The journey takes about 1 day, 1 hour 15 minutes and with fares starting at just $77, it presents an excellent value for a comfortable ride.

22bus per day
1d 1hAverage Duration
889 milesDistance
36kgCO₂ emissions

Frequently asked questions about traveling from Gainesville, FL to Chicago by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/12
$80
11/13
No data
Today
$228
11/15
$116
11/16
$136
11/17
No data
11/18
No data
11/19
No data
busbud logoThe cheapest trip from Gainesville, FL to Chicago was searched and found on Nov 12, 2025 with a price of $80

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Chicago, as early as possible.

You can expect to pay from $80 to $254 for a bus ticket from Gainesville, FL to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $116 which is on 2025-11-15.

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