Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Avignon (Le Pontet) | Brussels-South (Gare du Midi) | CheapestFastest | ||||
| Bus | Avignon (Le Pontet) | Brussels-South (Gare du Midi) | No tags |
Last refresh of the prices: Today at 11:37 AM CET.
Compare 3 ways to go from Avignon to Brussels
Among the sustainable travel choices, the carpool stands out as the good way to reach Brussels. The journey takes about 10 hours 30 minutes and with fares starting at just $108, it presents an excellent value for a comfortable ride.
Where are the popular stops in Avignon and Brussels?
Stops in Avignon
- A
Gare Routière Avignon
54 Boulevard Saint-Roch, 84000 Avignon, France - B
Parking St. Bénézet
Boulevard du Rhône, 84000 Avignon, France - C
Avignon (TGV-Station)
Place de l'Europe, 84000 Avignon, France - D
Avignon (Bus Station)
42 Boulevard Saint-Roch, 84000 Avignon, France
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- CPachecolaan 5, 1000 Brussel, Belgium
- D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
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Frequently asked questions about traveling from Avignon to Brussels by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Avignon to Brussels?
The cheapest bus tickets from Avignon to Brussels start from $50. The average price for this route is around $81. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Avignon to Brussels?
The average bus trip duration from Avignon to Brussels is 15h 5m, covering a distance of 475 miles (766 km). The quickest bus can get you there in 12h 40m and is operated by BlaBlaCar Bus.
Which bus companies service the Avignon to Brussels route?
Several major bus companies operate on this route with 2 buses available per day, including services from FlixBus, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Avignon to Brussels?
The earliest bus departs from Avignon to Brussels at 12:10am. And the latest bus departs at 10:20pm.
What are the CO₂ emissions for the bus trip from Avignon to Brussels?
A bus trip from Avignon to Brussels generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Avignon to Brussels?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11143 reviews.
Which bus company has the best Wi-Fi from Avignon to Brussels?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Avignon to Brussels?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Avignon to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Avignon to Brussels was searched and found on Dec 3, 2025 with a price of $51To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Avignon to Brussels, as early as possible.
You can expect to pay from $51 to $118 for a bus ticket from Avignon to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $51 which is on 2025-12-03.
What's the cheapest way to go from Avignon to Brussels?
The bus is the cheapest travel choice for this destination
