Find coaches from San Luis Obispo to San Francisco, US

Next departures

Next departures from San Luis Obispo to San Francisco on 1 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Amtrak
Cal Poly Vista Grande Dining Complex
Mission St & Fremont StCheapestFastest
Amtrak
AMTRAK Station
Mission St & Fremont StNo tags
Amtrak
AMTRAK Station
Mission St & Fremont StNo tags
Amtrak
Cal Poly Vista Grande Dining Complex
Mission St & Fremont StNo tags

Last refresh of the prices: Yesterday at 2:58 AM PDT.

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Get from San Luis Obispo to San Francisco

busbud logoThis route is served by bus only

The journey takes about 4 hours 35 minutes, and with fares starting at just US$16, it presents an excellent value for a comfortable ride.

1bus per day
4h 35mAverage duration
319 kmDistance
8kgCO₂ emissions

Bus San Luis Obispo to San Francisco, US: Trip Overview

Average ticket priceUS$51
Average bus trip duration4h 35m
Number of daily buses1
Earliest bus departure00:30
Distance319 km
Latest bus departure16:35

San Luis Obispo to San Francisco Bus

With Busbud, comparing and booking tickets for a bus from San Luis Obispo to San Francisco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Luis Obispo to San Francisco from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from San Luis Obispo to San Francisco, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Luis Obispo - San Francisco, US

  1. How much does a bus ticket from San Luis Obispo to San Francisco cost?

    The bus ticket price from San Luis Obispo to San Francisco starts at US$16. The best way to find cheap bus tickets from San Luis Obispo to San Francisco is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from San Luis Obispo to San Francisco?

    The average travel time between San Luis Obispo and San Francisco is around 4h 35m, although the fastest bus will take about 4h 10m. This is the time it takes to travel the 326 km that separates the two cities.

  3. How many daily bus connections are there between San Luis Obispo and San Francisco?

    The number of buses from San Luis Obispo to San Francisco can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from San Luis Obispo to San Francisco by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from San Luis Obispo to San Francisco?

    When taking the bus from San Luis Obispo to San Francisco, you can travel comfortably and safely with Amtrak, FlixBus.

  5. What are the departure and arrival stations when taking the bus from San Luis Obispo to San Francisco?

    Buses travelling between San Luis Obispo and San Francisco leave from AMTRAK Station or San Luis Obispo Bus Stop and arrive at Hyde/Beach (Fisherman's Wharf), Powell Station, Union Square Hilton.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$85
29/10
US$85
Today
US$85
31/10
US$55
01/11
US$85
02/11
US$85
03/11
No data
04/11
US$34
busbud logoThe cheapest trip from San Luis Obispo to San Francisco, US was searched and found on 04 Nov 2025 with a price of US$34

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis Obispo to San Francisco, US as early as possible.

You can expect to pay from US$34 to US$107 for a bus ticket from San Luis Obispo to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$34, which is on 2025-11-04.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Luis Obispo to San Francisco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Luis Obispo to San Francisco, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Luis Obispo to San Francisco that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from San Luis Obispo to San Francisco, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to San Luis Obispo by bus?

Bus from San Francisco, US to San Luis Obispo

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