Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 199 Spring Garden St. | Gateway Station | Cheapest | ||||
| Bus | 199 Spring Garden St. | Gateway Station | Fastest | ||||
| Bus | 199 Spring Garden St. | Gateway Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Philadelphia, 199 Spring Garden St | Gateway Station | No tags | ||||
| Bus | 199 Spring Garden St. | Gateway Station | No tags |
Last refresh of the prices: Yesterday at 2:43 PM EST.
Compare 2 ways to travel from Philadelphia to St. Louis
Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 3 hours 55 minutes and with fares starting at just R 1 618, it presents an excellent value for a comfortable ride.
Where are the popular stops in Philadelphia and St. Louis?
Stops in Philadelphia
- A
Philadelphia Airport
- BOff of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
- C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA - D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA - E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA - F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
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Frequently asked questions about travelling from Philadelphia, PA to St. Louis by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Philadelphia to St. Louis?
The cheapest bus tickets from Philadelphia to St. Louis start at R 1 618. The average price for this route is around R 2 788. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Philadelphia to St. Louis?
The average bus journey time from Philadelphia to St. Louis is 1d 3h, covering a distance of 1300 km. The fastest bus gets you there in 20h 30m and is operated by Greyhound.
Which bus companies service the Philadelphia to St. Louis route?
What is the earliest and latest departure time for the bus from Philadelphia to St. Louis?
The earliest bus departs from Philadelphia to St. Louis at 02:00. And the latest bus departs at 23:15.
What are the CO₂ emissions for the bus trip from Philadelphia to St. Louis?
A bus trip from Philadelphia to St. Louis produces an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Philadelphia to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Philadelphia to St. Louis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Philadelphia to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Philadelphia to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Philadelphia, PA to St. Louis was searched and found on 08 Dec 2025 with a price of R 1 502To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to St. Louis as early as possible.
You can expect to pay from R 1 502 to R 5 657 for a bus ticket from Philadelphia, PA to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 502, which is on 2025-12-08.
What's the cheapest way to go from Philadelphia, PA to St. Louis?
The bus is the cheapest travel choice for this destination
