Bus from Lyon to Brussels: Tickets & Timetables

Next bus departures

Next departures from Lyon to Brussels on 5 February
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
BlaBlaCar BusBus
    Lyon (Gerland)
    Brussels-South (Gare du Midi)Cheapest
    BlaBlaCar BusBus
      Lyon (Gerland)
      Brussels-South (Gare du Midi)Fastest
      BlaBlaCar BusBus
        Lyon (Gerland)
        Brussels North Train StationNo tags
        FlixbusBus
        Aéroport LYS
        Brussels North Train StationNo tags
        BlaBlaCar BusBus
          Lyon (Gerland)
          Brussels-South (Gare du Midi)No tags

          Last refresh of the prices: Today at 6:32 PM CET.

          Compare 3 ways to travel from Lyon to Brussels

          We recommend taking the train

          Among the sustainable travel choices, the Train stands out as a good way to reach Brussels. The journey takes about 4 hours 13 minutes and with fares starting at just R 1 133, it presents an excellent value for a comfortable ride.

          19train per day
          4h 13mAverage duration
          566 kmDistance
          14kgCO₂ emissions
          Average priceR 401 - R 3 450Average duration11h 25m
          14kg CO₂e
          Train
          Average priceR 1 133 - R 4 354Average duration4h 13m
          14kg CO₂e
          Carpool
          Average priceR 587 - R 1 776Average duration7h 40m
          24kg CO₂e

          Frequently asked questions about travelling from Lyon to Brussels by bus

          Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

          1. How much is the bus ticket from Lyon to Brussels?

            The cheapest bus tickets from Lyon to Brussels start at R 401. The average price for this route is around R 744. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

          2. How long is the bus journey from Lyon to Brussels?

            The average bus journey time from Lyon to Brussels is 11h 25m, covering a distance of 567 km. The fastest bus gets you there in 8h 40m and is operated by BlaBlaCar Bus.

          3. Which bus companies service the Lyon to Brussels route?

            Several major bus companies operate on this route with 23 buses available per day, including services from FlixBus, BlaBlaCar Bus.

          4. What is the earliest and latest departure time for the bus from Lyon to Brussels?

            The earliest bus departs from Lyon to Brussels at 00:10. And the latest bus departs at 23:59.

          5. What are the CO₂ emissions for the bus trip from Lyon to Brussels?

            A bus trip from Lyon to Brussels produces an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

          6. What is the best bus company from Lyon to Brussels?

            According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11385 reviews.

          7. Which bus company has the best Wi-Fi from Lyon to Brussels?

            Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

          8. Which bus company offers the most punctual service from Lyon to Brussels?

            According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

          9. Which bus company has the cleanest buses from Lyon to Brussels?

            According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.

          Find cheapest prices for buses

          Price is for a one-way ticket for one passenger and based on past searches.

          Best price found
          02/02
          R 934
          03/02
          R 677
          Today
          R 974
          05/02
          R 418
          06/02
          R 418
          07/02
          R 577
          08/02
          R 418
          09/02
          R 398
          busbud logoThe cheapest trip from Lyon to Brussels was searched and found on 09 Feb 2026 with a price of R 398

          To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Brussels as early as possible.

          You can expect to pay from R 398 to R 2 886 for a bus ticket from Lyon to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at R 398, which is on 2026-02-09.

          Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

          What's the cheapest way to go from Lyon to Brussels?

          busbud logoThe Bus is the cheapest travel choice for this destination

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