Bus from Lyon to Brussels: Tickets & Timetables

Next bus departures

Next departures from Lyon to Brussels on 1 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixbusBus
Perrache
Brussels North Train StationCheapest
BlaBlaCar BusBus
    		Lyon - Perrache Bus Station
    		Brussels-South (Gare du Midi)Fastest
    BlaBlaCar BusBus
      		Lyon - Perrache Bus Station
      		Brussels-South (Gare du Midi)No tags
      FlixbusBus
      		Aéroport LYS
      		Brussels North Train StationNo tags
      BlaBlaCar BusBus
        		Lyon - Perrache Bus Station
        		Brussels-South (Gare du Midi)No tags

        Last refresh of the prices: Today at 16:57 CET.

        Compare 3 ways to travel from Lyon to Brussels

        We recommend taking the train

        Among the sustainable travel choices, the train stands out as a good way to reach Brussels. The journey takes about 4 hours 13 minutes and with fares starting at just £54, it presents an excellent value for a comfortable ride.

        19train per day
        4h 13mAverage duration
        351 milesDistance
        14kgCO₂ emissions
        Bus
        		Average price£21 - £143Average duration11h 55m
        14kg CO₂e
        Train
        		Average price£54 - £205Average duration4h 13m
        14kg CO₂e
        Carpool
        		Average price£35 - £85Average duration7h 30m
        24kg CO₂e

        Frequently asked questions about travelling by bus from Lyon to Brussels

        Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

        1. How much is the bus ticket from Lyon to Brussels?

          The cheapest coach tickets from Lyon to Brussels start from £21. The average price for this route is around £44. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

        2. How long is the bus journey from Lyon to Brussels?

          The average bus journey time from Lyon to Brussels is 11h 55m, covering a distance of 352 miles. The fastest bus can take you there in 8h 40m and is operated by BlaBlaCar Bus.

        3. Which bus companies service the Lyon to Brussels route?

          Several major bus companies operate on this route with 15 buses available per day, including services from FlixBus, BlaBlaCar Bus.

        4. What is the earliest and latest departure time for the bus from Lyon to Brussels?

          The earliest bus departs from Lyon to Brussels at 00:20. And the latest bus departs at 23:59.

        5. What are the CO₂ emissions for the bus trip from Lyon to Brussels?

          A bus journey from Lyon to Brussels produces an estimated 14 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

        6. Which is the best bus company from Lyon to Brussels?

          According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11143 reviews.

        7. Which company has the best Wi-Fi from Lyon to Brussels?

          Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

        8. Which bus company offers the most punctual service from Lyon to Brussels?

          According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

        9. Which bus company has the cleanest buses from Lyon to Brussels?

          According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.

        Find cheapest prices for buses

        Price is for a one-way ticket for one passenger and based on past searches.

        Best price found
        28/11
        £45
        29/11
        £37
        Today
        £38
        01/12
        £31
        02/12
        £28
        03/12
        £27
        04/12
        £27
        05/12
        £28
        busbud logoThe cheapest trip from Lyon to Brussels was searched and found on 3 Dec 2025 with a price of £27

        To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Brussels as early as possible.

        You can expect to pay from £27 to £89 for a bus ticket from Lyon to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at £27, which is on 2025-12-03.

        What's the cheapest way to go from Lyon to Brussels?

        busbud logoThe bus is the cheapest travel choice for this destination

        People from around the world trust Busbud

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