Train from Brussels to Prague: Tickets & Timetables

Next train departures

Next departures from Brussels to Prague on 8 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
European SleeperTrain
    		Brussels South/Midi Train Station
    		Hlavní nádražíCheapest
    European SleeperTrain
      		Brussels South/Midi Train Station
      		Hlavní nádražíFastest
      European SleeperTrain
        		Brussels South/Midi Train Station
        		Hlavní nádražíNo tags
        European SleeperTrain
          		Brussels South/Midi Train Station
          		Hlavní nádražíNo tags
          European SleeperTrain
            		Brussels South/Midi Train Station
            		Hlavní nádražíNo tags

            Last refresh of the prices: Today at 20:27 CET.

            Compare 2 ways to travel from Brussels to Prague

            We recommend taking the bus

            Among the sustainable travel choices, the bus stands out as a good way to reach Prague. The journey takes about 19 hours 15 minutes and with fares starting at just £34, it presents an excellent value for a comfortable ride.

            28bus per day
            19h 15mAverage duration
            445 milesDistance
            18kgCO₂ emissions
            Bus
            		Average price£34 - £156Average duration19h 15m
            18kg CO₂e
            Train
            		Average price£49 - £227Average duration14h 36m
            17kg CO₂e

            Frequently asked questions about travelling from Brussels to Prague by train

            Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

            1. How much does a train ticket cost from Brussels to Prague?

              The cheapest train tickets from Brussels to Prague start from £49. The average price for this train route is around £111. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

            2. How long is the train journey from Brussels to Prague?

              The average train journey time from Brussels to Prague is 14h 36m, covering a distance of 445 miles. The fastest train gets you there in 12h 47m and is operated by Deutsche Bahn.

            3. Which train operators serve the Brussels to Prague route?

              Several major train operators run on this route with 5 trains available per day.

            4. What are the earliest and latest departure times for the train from Brussels to Prague?

              The earliest train from Brussels to Prague departs at 06:01. And the latest train departs at 22:01.

            Find cheapest prices for trains

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            03/12
            £192
            04/12
            No data
            Today
            £193
            06/12
            No data
            07/12
            No data
            08/12
            £221
            09/12
            No data
            10/12
            £138
            busbud logoThe cheapest trip from Brussels to Prague was searched and found on 10 Dec 2025 with a price of £138

            To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Brussels to Prague as early as possible.

            You can expect to pay from £138 to £1,147 for a train ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at £138, which is on 2025-12-10.

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