Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Brussels South/Midi Train Station | Hlavní nádraží | Cheapest | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | Fastest | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags |
Last refresh of the prices: Today at 8:27 PM CET.
Compare 2 ways to go from Brussels to Prague
Among the sustainable travel choices, the bus stands out as a good way to reach Prague. The journey takes about 19 hours 15 minutes, and with fares starting at just $63, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Brussels and Prague?
Brussels
- ABoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- BRue de France 85, 1060 Saint-Gilles, Belgium
- C
Bruxelles / Brussels Central
Brussel-Centraal, Carrefour de l'Europe, 1000 Bruxelles, Belgium
Prague
- A300/8 Wilsonova, 110 00 Praha, Czechia
- BKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- CAviatická, 161 08, Praha 6, Czechia
- DChlumecká, 198 00 Praha 20, Czech Republic
- ETomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- F
Praha-Smichov
Praha-Smíchov, 150 00 Praha-Praha 5, Czechia
Train companies
Based on 6 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the power outlets and the ticket access but often complained with the timeliness. Deutsche Bahn ticket prices on this trip start at $338
Frequently asked questions about travelling from Brussels to Prague by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Brussels to Prague?
The cheapest train tickets from Brussels to Prague start at $91. The average price for this train route is around $205. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Brussels to Prague?
The average train trip from Brussels to Prague takes 14h 36m and covers 717 km. The quickest train gets you there in 12h 47m and is operated by Deutsche Bahn.
Which train operators serve the Brussels to Prague route?
Several major train operators serve this route, with 5 trains available per day.
What are the earliest and latest departure times for the train from Brussels to Prague?
The earliest train from Brussels to Prague departs at 6:01am. The latest train departs at 10:01pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Prague was searched and found on Dec 10, 2025 with a price of $254To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Brussels to Prague, as early as possible.
You can expect to pay from $254 to $2,120 for a train ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $254 which is on 2025-12-10.
