Find coaches from Syracuse, US to Chicago

Next departures

Next departures from Syracuse to Chicago on 30 September
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
Chicago 95Th & Dan RyanCheapest
Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
Downtown Greyhound StationFastest
Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
Downtown Greyhound StationNo tags
FlixBus + Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
Downtown Greyhound StationNo tags
Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
537-517 W. Jackson BlvdNo tags

Last refresh of the prices: Yesterday at 23:19 EDT.

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Compare 2 ways to travel from Syracuse to Chicago

Bus
Average priceUS$60 - US$221Average duration1d 3h
24kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$60 - US$215Average duration13h 7m
86kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Syracuse to Chicago

Among the sustainable travel choices, the train stands out as a good way to reach Chicago. The journey takes about 13 hours 7 minutes and with fares starting at just US$60, it presents an excellent value for a comfortable ride.

1train per day
13h 7mAverage duration
US$60Cheapest ticket
86kgCO₂ emissions

Bus Syracuse, US to Chicago: Trip Overview

Average ticket priceUS$93
Average bus trip duration1d 3h
Number of daily buses7
Earliest bus departure04:30
Distance589 miles
Latest bus departure21:00

Syracuse to Chicago Bus

Busbud helps you find a bus from Syracuse to Chicago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Syracuse to Chicago from the most reliable bus companies operating this trip.

Discover how much the bus trip from Syracuse to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Syracuse, US - Chicago

  1. How far is Chicago from Syracuse by coach?

    The distance between Syracuse and Chicago by coach is approximately 592 miles (954 km).

  2. Is there a way to reach Chicago from Syracuse without flying?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
27/09
US$148
28/09
US$65
Today
US$111
30/09
US$63
01/10
US$58
02/10
US$60
03/10
US$60
04/10
US$65
busbud logoThe cheapest trip from Syracuse, US to Chicago was searched and found on 1 Oct 2025 with a price of US$58

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Chicago as early as possible.

You can expect to pay from US$58 to US$324 for a bus ticket from Syracuse, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$58, which is on 2025-10-01.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Syracuse and Chicago!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Syracuse to Chicago, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Syracuse to Chicago will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Syracuse to Chicago.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Syracuse, US to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Syracuse, US by bus?

Bus from Chicago to Syracuse, US

You can also go to Chicago by train

Train from Syracuse, US to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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