Find coaches from Pittsburgh to Knoxville, TN

Previously seen journeys

Next departures from Pittsburgh to Knoxville on 2 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Pittsburgh Intermodal Station
Knoxville Bus StationNo tags
Greyhound
Pittsburgh Intermodal Station
Knoxville Bus StationNo tags
Greyhound
Pittsburgh Intermodal Station
Knoxville Bus StationNo tags
Greyhound
Pittsburgh Intermodal Station
Knoxville Bus StationNo tags
Greyhound
Pittsburgh Intermodal Station
Knoxville Bus StationNo tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Pittsburgh to Knoxville, TN: Trip Overview

Average ticket priceUS$91
Average bus trip duration17h 40m
Number of daily buses2
Earliest bus departure01:35
Distance372 miles
Latest bus departure21:00

Pittsburgh to Knoxville Bus

With Busbud, comparing and booking tickets for a bus from Pittsburgh to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Pittsburgh to Knoxville will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Pittsburgh to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Pittsburgh - Knoxville, TN

  1. How far is Knoxville from Pittsburgh by coach?

    The distance between Pittsburgh and Knoxville by coach is approximately 376 miles (606 km).

  2. What is the best way to go from Pittsburgh to Knoxville without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/09
US$65
01/10
No data
Today
No data
03/10
No data
04/10
No data
05/10
No data
06/10
No data
07/10
No data
busbud logoThe cheapest trip from Pittsburgh to Knoxville, TN was searched and found on 30 Sept 2025 with a price of US$65

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Knoxville, TN as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Pittsburgh to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Pittsburgh to Knoxville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Pittsburgh to Knoxville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Pittsburgh to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Pittsburgh by bus?

Bus from Knoxville, TN to Pittsburgh

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Pittsburgh

Buses Leaving from Pittsburgh

Buses Going to Pittsburgh

Popular Buses Connecting Knoxville

Buses Leaving from Knoxville

Buses Going to Knoxville