Find coaches from Indianapolis to Knoxville, TN

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Fri8 Aug
from US$84
Sat9 Aug
from US$77
Sun10 Aug
Mon11 Aug
from US$65
Tue12 Aug
Wed13 Aug
Thu14 Aug
Fri15 Aug

Cheap buses leaving Saturday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 9 August at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 9 August at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 9 August at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 9 August at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 9 August at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 9 August at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 9 August at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 9 August at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Indianapolis to Knoxville, TN: Trip Overview

Average ticket priceUS$84
Average bus trip duration11h 15m
Number of daily buses2
Earliest bus departure04:50
Distance288 miles
Latest bus departure11:25

Indianapolis to Knoxville Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Indianapolis to Knoxville will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Knoxville from Indianapolis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Indianapolis - Knoxville, TN

  1. How far is Knoxville from Indianapolis by coach?

    The journey from Indianapolis to Knoxville by coach covers an approximate distance of 290 miles (468 km).

  2. Is there a way to reach Knoxville from Indianapolis without flying?

    To travel from Indianapolis to Knoxville without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/08
US$78
05/08
US$130
Today
US$116
07/08
US$70
08/08
US$76
09/08
US$69
10/08
No data
11/08
US$59
busbud logoThe cheapest trip from Indianapolis to Knoxville, TN was searched and found on 11 Aug 2025 with a price of US$59

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Knoxville, TN as early as possible.

You can expect to pay from US$59 to US$171 for a bus ticket from Indianapolis to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at US$59, which is on 2025-08-11.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Indianapolis to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Indianapolis to Knoxville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Indianapolis to Knoxville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Indianapolis to Knoxville.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Knoxville, TN

Why choose Busbud?

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