Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | University of South Florida | Cheapest | ||||
 | Bus | Bus station | Tampa Bus Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Tampa Bus Station | No tags | ||||
 | Bus | Bus station | Tampa Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | University of South Florida | No tags |
Last refresh of the prices: Last Saturday at 20:38 EST.
Compare 2 ways to travel from Florence to Tampa
Among the sustainable travel choices, the train stands out as a good way to reach Tampa. The journey takes about 18 hours 30 minutes and with fares starting at just £74, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Tampa?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Tampa
- A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605 - B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA - C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA - D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA - E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA - F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA
Compare bus companies
Frequently asked questions about travelling by bus from Florence, SC, US to Tampa
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Florence to Tampa?
The cheapest coach tickets from Florence to Tampa start from £50. The average price for this route is around £90. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Florence to Tampa?
The average bus journey time from Florence to Tampa is 20h 50m, covering a distance of 459 miles. The fastest bus can take you there in 14h and is operated by FlixBus.
Which bus companies service the Florence to Tampa route?
What is the earliest and latest departure time for the bus from Florence to Tampa?
The earliest bus departs from Florence to Tampa at 05:45. And the latest bus departs at 16:30.
What are the CO₂ emissions for the bus trip from Florence to Tampa?
A bus journey from Florence to Tampa produces an estimated 18 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Florence to Tampa?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which company has the best Wi-Fi from Florence to Tampa?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Florence to Tampa?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Tampa?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Tampa was searched and found on 4 Dec 2025 with a price of £63To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Tampa as early as possible.
You can expect to pay from £63 to £137 for a bus ticket from Florence, SC, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at £63, which is on 2025-12-04.
Usually Greyhound, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Florence, SC, US to Tampa?
The bus is the cheapest travel choice for this destination
