Bus from Florence, SC, US to Tampa: Tickets & Schedules

Previously seen trips

Next departures for Florence to Tampa on November 29
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Bus
Bus station
Tampa Bus StationNo tags
GreyhoundBus
Bus station
Tampa Bus StationNo tags
Greyhound + FlixBus
Bus
Florence, SC
Tampa Bus StationNo tags
Greyhound + FlixBus
Bus
Bus station
Tampa Bus StationNo tags
FlixBus + Greyhound
Bus
Bus station
University of South FloridaNo tags

Compare 2 ways to go from Florence to Tampa

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Tampa. The journey takes about 18 hours 30 minutes and with fares starting at just $95, it presents an excellent value for a comfortable ride.

1train per day
18h 30mAverage Duration
460 milesDistance
67kgCO₂ emissions
Average Price$65 - $229Average Duration20h 50m
18kg CO₂e
Average Price$95 - $207Average Duration18h 30m
67kg CO₂e

Frequently asked questions about traveling from Florence, SC, US to Tampa by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Florence to Tampa?

    The cheapest bus tickets from Florence to Tampa start from $65. The average price for this route is around $117. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Florence to Tampa?

    The average bus trip duration from Florence to Tampa is 20h 50m, covering a distance of 459 miles (739 km). The quickest bus can get you there in 14h and is operated by FlixBus.

  3. Which bus companies service the Florence to Tampa route?

    Several major bus companies operate on this route with 5 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Florence to Tampa?

    The earliest bus departs from Florence to Tampa at 4:45am. And the latest bus departs at 4:30pm.

  5. What are the CO₂ emissions for the bus trip from Florence to Tampa?

    A bus trip from Florence to Tampa generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Florence to Tampa?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.

  7. Which bus company has the best Wi-Fi from Florence to Tampa?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Florence to Tampa?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Florence to Tampa?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/27
$95
11/28
$102
Today
$166
11/30
$119
12/01
$108
12/02
$90
12/03
$80
12/04
$80
busbud logoThe cheapest trip from Florence, SC, US to Tampa was searched and found on Dec 4, 2025 with a price of $80

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Tampa, as early as possible.

You can expect to pay from $80 to $220 for a bus ticket from Florence, SC, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $80 which is on 2025-12-04.

Usually Greyhound, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Florence, SC, US to Tampa?

busbud logoThe bus is the cheapest travel choice for this destination

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