How much is the bus ticket from Florence to Tampa?

The cheapest bus tickets from Florence to Tampa start from $65. The average price for this route is around $117. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Florence to Tampa?

The average bus trip duration from Florence to Tampa is 20h 50m, covering a distance of 459 miles (739 km). The quickest bus can get you there in 14h and is operated by FlixBus .

Which bus companies service the Florence to Tampa route?

Several major bus companies operate on this route with 5 buses available per day, including services from FlixBus , Greyhound .

What is the earliest and latest departure time for the bus from Florence to Tampa?

The earliest bus departs from Florence to Tampa at 4:45am. And the latest bus departs at 4:30pm.

What are the CO₂ emissions for the bus trip from Florence to Tampa?

A bus trip from Florence to Tampa generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Florence to Tampa?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11380 reviews.

Which bus company has the best Wi-Fi from Florence to Tampa?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Florence to Tampa?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Florence to Tampa?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Florence to Tampa from $80 | Refundable Tickets

Previously seen trips

Next departures for Florence to Tampa on November 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	12:55pm	Bus station	21h 20m	10:15am	Tampa Bus Station	No tags
	Bus	4:15pm	Bus station	1d 1h	6:10pm	Tampa Bus Station	No tags
Greyhound + FlixBus	Bus	5:35am	Florence, SC	11h 20m	4:55pm	Tampa Bus Station	No tags
Greyhound + FlixBus	Bus	12:55pm	Bus station	17h 5m	6:00am	Tampa Bus Station	No tags
FlixBus + Greyhound	Bus	12:55pm	Bus station	20h 50m	9:45am	University of South Florida	No tags

Compare 2 ways to go from Florence to Tampa

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Tampa. The journey takes about 18 hours 30 minutes and with fares starting at just $95, it presents an excellent value for a comfortable ride.

1train per day

18h 30mAverage Duration

460 milesDistance

67kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$65 - $229	Average Duration20h 50m	CO₂ emissions 18kg CO₂e
Train	Average Price$95 - $207	Average Duration18h 30m	CO₂ emissions 67kg CO₂e

Where are the popular stops in Florence and Tampa?

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Tampa

A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605
B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA
C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA
D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA
E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA
F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA

Compare bus companies

FlixBus

3.5/511,472 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,407 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Florence, SC, US to Tampa by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Florence to Tampa?
The cheapest bus tickets from Florence to Tampa start from $65. The average price for this route is around $117. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Tampa?
The average bus trip duration from Florence to Tampa is 20h 50m, covering a distance of 459 miles (739 km). The quickest bus can get you there in 14h and is operated by FlixBus.
Which bus companies service the Florence to Tampa route?
Several major bus companies operate on this route with 5 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Florence to Tampa?
The earliest bus departs from Florence to Tampa at 4:45am. And the latest bus departs at 4:30pm.
What are the CO₂ emissions for the bus trip from Florence to Tampa?
A bus trip from Florence to Tampa generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Florence to Tampa?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which bus company has the best Wi-Fi from Florence to Tampa?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Florence to Tampa?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Tampa?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/27

$95

11/28

$102

Today

$166

11/30

$119

12/01

$108

12/02

$90

12/03

$80

12/04

$80

The cheapest trip from Florence, SC, US to Tampa was searched and found on Dec 4, 2025 with a price of $80

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Tampa, as early as possible.

You can expect to pay from $80 to $220 for a bus ticket from Florence, SC, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $80 which is on 2025-12-04.

Usually Greyhound, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.