Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | Cheapest | ||||
| Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | Fastest | ||||
| Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | No tags |
Last refresh of the prices: Today at 20:08 EST.
Get from Detroit to Tupelo
The journey takes about 23 hours 45 minutes, and with fares starting at just £93, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87422 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £93
Frequently asked questions about travelling by bus from Detroit, MI to Tupelo
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Detroit to Tupelo?
The cheapest coach tickets from Detroit to Tupelo start from £93. The average price for this route is around £124. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Detroit to Tupelo?
The average bus journey time from Detroit to Tupelo is 23h 45m, covering a distance of 636 miles. The fastest bus can take you there in 19h 20m and is operated by Greyhound.
Which bus companies service the Detroit to Tupelo route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Detroit to Tupelo?
The earliest bus departs from Detroit to Tupelo at 06:40. And the latest bus departs at 23:25.
What are the CO₂ emissions for the bus trip from Detroit to Tupelo?
A bus journey from Detroit to Tupelo produces an estimated 26 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Tupelo was searched and found on 11 Dec 2025 with a price of £104To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Tupelo as early as possible.
You can expect to pay from £104 to £156 for a bus ticket from Detroit, MI to Tupelo based on the last 2 days. You can expect to find the cheapest price for the trip at £104, which is on 2025-12-11.
