Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
FlixBus + Greyhound | Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | No tags |
Get from Detroit to Tupelo
The journey takes about 1 day, 10 minutes, and with fares starting at just $146, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87531 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $146
Frequently asked questions about travelling from Detroit, MI to Tupelo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Detroit to Tupelo?
The cheapest bus tickets from Detroit to Tupelo start from $146. The average price for this route is around $175. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
Which bus companies service the Detroit to Tupelo route?
Several major bus companies operate on this route with 3 buses available per day.
What are the earliest and latest departure times for the bus from Detroit to Tupelo?
The earliest bus departs from Detroit to Tupelo at 7:15am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Detroit to Tupelo?
A bus trip from Detroit to Tupelo generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Tupelo was searched and found on Mar 24, 2026 with a price of $152To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Tupelo, as early as possible.
You can expect to pay from $152 to $166 for a bus ticket from Detroit, MI to Tupelo based on the last 2 days. You can expect to find the cheapest price for the trip at $164 which is on 2026-03-28.
