Trains leaving Saturday
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: June 7 atDeparture city: JacksonvilleDeparture location: Jacksonville Amtrak StationArrival time: June 9 atDestination city: BuffaloDestination location: Depew StationOperated by: Amtrak
Vehicle: TrainDuration: - This trip is recommended because it is the: FastestDeparture time: June 7 atDeparture city: JacksonvilleDeparture location: Jacksonville Amtrak StationArrival time: June 8 atDestination city: BuffaloDestination location: Depew StationOperated by: AmtrakVehicle: TrainDuration:
- Departure time: June 7 atDeparture city: JacksonvilleDeparture location: Jacksonville Amtrak StationArrival time: June 8 atDestination city: BuffaloDestination location: Depew StationOperated by: AmtrakVehicle: TrainDuration:
- Departure time: June 7 atDeparture city: JacksonvilleDeparture location: Jacksonville Amtrak StationArrival time: June 8 atDestination city: BuffaloDestination location: Depew StationOperated by: AmtrakVehicle: TrainDuration:
- Departure time: June 7 atDeparture city: JacksonvilleDeparture location: Jacksonville Amtrak StationArrival time: June 9 atDestination city: BuffaloDestination location: Depew StationOperated by: AmtrakVehicle: TrainDuration:
Last refresh of the prices: Last Sunday at 8:56 PM EDT.
Prices and availability are subject to change.
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Compare 2 ways to go from Jacksonville to Buffalo
Busbud recommends taking the bus from Jacksonville to BuffaloAmong the sustainable travel choices, the bus stands out as a good way to reach Buffalo. The journey takes about 1 day, 5 hours 55 minutes, and with fares starting at just US$90, it presents an excellent value for a comfortable ride.
Train Jacksonville to Buffalo: Trip Overview
Please note, this information is subject to change
Train companies
Based on 5171 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at US$217.00
Jacksonville to Buffalo Train
With Busbud, comparing and booking tickets for a train from Jacksonville to Buffalo is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
We make sure you can find a train service from Jacksonville to Buffalo from the most reliable train companies operating this trip.
Whether it is train tickets or first class train tickets going to Buffalo from Jacksonville, we help you find what you're looking for based on how much of a budget you have.
Where are the popular train stations and stops in Jacksonville (FL) and Buffalo (NY)?
Frequently asked questions on the trip Jacksonville (FL) - Buffalo (NY)
How much does a cheap train ticket from Jacksonville to Buffalo cost?
The average train ticket price from Jacksonville to Buffalo is US$355. The best way to find cheap train tickets from Jacksonville to Buffalo is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the trip from Jacksonville to Buffalo?
A train trip between Jacksonville and Buffalo is around 1d 4h, although the fastest train will take about 1d 4h. This is the time it takes to travel the 1420 km that separates the two cities.
How many daily trains are there between Jacksonville and Buffalo?
The number of trains from Jacksonville to Buffalo can differ depending on the day of the week. On average, there are 2. Some trains are direct while others include transferring trains. Simplify your train trip from Jacksonville to Buffalo by comparing and selecting the train that fits your travel style and budget on Busbud.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville to Buffalo was searched and found on Jun 10, 2025 with a price of US$302To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Jacksonville to Buffalo, as early as possible.
You can expect to pay from US$302 to US$1,386 for a train ticket from Jacksonville to Buffalo based on the last 2 days. You can expect to find the cheapest price for the trip at US$302 which is on 2025-06-10.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Jacksonville to Buffalo is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Regional train? High-speed train? Whichever train to Buffalo you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
By choosing the train between Jacksonville and Buffalo, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Create your real-life musical score by curating a personalized train travel playlist - the perfect accompaniment to your train ride from Jacksonville to Buffalo.
Did you know?
You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.
The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while travelling more than 17,000 km.
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one travelling between the city and the suburbs.
Top Travelled Train Routes
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