Trains tickets from Jacksonville (FL) to Buffalo (NY)

Discover your next train travel journey from Jacksonville (FL) to Buffalo (NY) and book online with ease

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Today3 Jun
Tomorrow4 Jun
Thu5 Jun
Fri6 Jun
Sat7 Jun
from US$366
Sun8 Jun
from US$374
Mon9 Jun
from US$374
Tue10 Jun
from US$314

Trains leaving Saturday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 7 June at
    Departure city: Jacksonville
    Departure location: Jacksonville Amtrak Station
    Arrival time: 9 June at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 7 June at
    Departure city: Jacksonville
    Departure location: Jacksonville Amtrak Station
    Arrival time: 8 June at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: 7 June at
    Departure city: Jacksonville
    Departure location: Jacksonville Amtrak Station
    Arrival time: 8 June at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: 7 June at
    Departure city: Jacksonville
    Departure location: Jacksonville Amtrak Station
    Arrival time: 8 June at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: 7 June at
    Departure city: Jacksonville
    Departure location: Jacksonville Amtrak Station
    Arrival time: 9 June at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

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Compare 2 ways to travel from Jacksonville to Buffalo

Bus
Average priceUS$90 - US$322Average duration1d 5h
35kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$217 - US$426Average duration1d 4h
129kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Jacksonville to Buffalo

Among the sustainable travel choices, the bus stands out as a good way to reach Buffalo. The journey takes about 1 day, 5 hours 55 minutes and with fares starting at just US$90, it presents an excellent value for a comfortable ride.

3bus per day
1d 5hAverage duration
US$90Cheapest ticket
35kgCO₂ emissions

Train Jacksonville to Buffalo: Trip Overview

Please note, this information is subject to change.

Average ticket priceUS$355
Average train trip duration1d 4h
Number of daily trains2
Earliest train departure17:11
Distance881 miles

Jacksonville to Buffalo Train

With Busbud, comparing and booking tickets for a train from Jacksonville to Buffalo is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.

We make sure you can find a train service from Jacksonville to Buffalo from the most reliable train companies operating this trip.

Whether it is train tickets or first class train tickets going to Buffalo from Jacksonville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Jacksonville (FL) - Buffalo (NY)

  1. How much does a cheap train ticket from Jacksonville to Buffalo cost?

    The average train ticket price from Jacksonville to Buffalo is US$355. The best way to find cheap train tickets from Jacksonville to Buffalo is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the train trip from Jacksonville to Buffalo?

    A train trip between Jacksonville and Buffalo is around 1d 4h, although the fastest train will take about 1d 4h. This is the time it takes to travel the 880 miles that separates the two cities.

  3. How many daily train are there between Jacksonville and Buffalo?

    The number of trains from Jacksonville to Buffalo can differ depending on the day of the week. On average, there are 2. Some trains are direct while others include transferring trains. Simplify your train trip from Jacksonville to Buffalo by comparing and selecting the train that fits your travel style and budget on Busbud.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/06
US$372
02/06
US$341
Today
No data
04/06
No data
05/06
No data
06/06
No data
07/06
US$352
08/06
US$360
busbud logoThe cheapest trip from Jacksonville to Buffalo was searched and found on 2 Jun 2025 with a price of US$341

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Jacksonville to Buffalo as early as possible.

You can expect to pay from US$341 to US$1,309 for a train ticket from Jacksonville to Buffalo based on the last 2 days. You can expect to find the cheapest price for the trip at US$352, which is on 2025-06-07.

About Train Travel

Train Travel Tips

Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Jacksonville to Buffalo is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.

Regional train? High-speed train? Whichever train to Buffalo you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.

By choosing the train between Jacksonville and Buffalo, you emit up to 30 times less CO2 than for the same journey made by plane or car!

Create your own real-life musical score by curating a personalised train travel playlist – the perfect accompaniment for your journey from Jacksonville to Buffalo.

Did you know?

You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.

The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while travelling more than 17,000 km.

You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one travelling between the city and the suburbs.

Will you be returning to Jacksonville by train?

Train from Buffalo to Jacksonville

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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Popular Trains Connecting Jacksonville

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