Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Wilmington Bus Station | Winston Salem Greyhound Bus Station | No tags | |||||
| Wilmington Bus Station | Winston Salem Greyhound Bus Station | No tags | |||||
| Wilmington Bus Station | Winston Salem Greyhound Bus Station | No tags | |||||
| Wilmington Bus Station | Winston Salem Greyhound Bus Station | No tags | |||||
| Wilmington Bus Station | Winston Salem Greyhound Bus Station | No tags |
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Compare 2 ways to go from Wilmington to Winston-Salem
| Average Price | Average Duration | CO₂ emissions | |||
|---|---|---|---|---|---|
| Average PriceUS$52 - US$124 | Average Duration17h 20m | 14kg CO₂e5 out of 5 stars | CheapestMost eco-friendly | ||
Train | Average PriceUS$225 - US$225 | Average Duration11h 15m | 52kg CO₂e1 out of 5 stars | Fastest |
Busbud recommends taking the train from Wilmington to Winston-SalemAmong the sustainable travel choices, the train stands out as a good way to reach Winston-Salem. The journey takes about 11 hours 15 minutes, and with fares starting at just US$225, it presents an excellent value for a comfortable ride.
Bus Wilmington, DE to Winston-Salem: Trip Overview
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Based on 87264 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at US$52
Wilmington to Winston-Salem Bus
Busbud helps you find a bus from Wilmington to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Wilmington to Winston-Salem.
From cheap bus tickets to more luxurious buses travelling from Wilmington to Winston-Salem, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Wilmington and Winston-Salem?
Frequently asked questions on the trip Wilmington, DE - Winston-Salem
How much does a bus ticket from Wilmington to Winston-Salem cost?
The bus ticket price from Wilmington to Winston-Salem starts at US$52. The best way to find cheap bus tickets from Wilmington to Winston-Salem is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Wilmington to Winston-Salem?
The average travel time between Wilmington and Winston-Salem is around 17h 20m, although the fastest bus will take about 11h 15m.This is the time it takes to travel the 577 km that separates the two cities.
How many daily bus connections are there between Wilmington and Winston-Salem?
The number of buses from Wilmington to Winston-Salem can differ depending on the day of the week. On average, there are 7 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Wilmington to Winston-Salem by comparing and selecting the bus that fits you travel style and budget on Busbud.
Which bus companies travel from Wilmington to Winston-Salem?
When taking the bus from Wilmington to Winston-Salem, you can travel comfortably and safely with Greyhound.
What are the departure and arrival stations when taking the bus from Wilmington to Winston-Salem?
Buses travelling between Wilmington and Winston-Salem leave from Wilmington Bus Station or Wilmington Station and arrive at Winston Salem Greyhound Bus Station, E Sprague St, Winston-Salem Bus Stop.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wilmington, DE to Winston-Salem was searched and found on Sep 18, 2025 with a price of US$44To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Winston-Salem, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Wilmington and Winston-Salem!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Wilmington to Winston-Salem.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Wilmington to Winston-Salem that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Wilmington to Winston-Salem.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
What's the cheapest way to go from Wilmington, DE to Winston-Salem?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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Popular Buses Connecting Wilmington
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Popular Buses Connecting Winston-Salem
Buses Leaving from Winston-Salem
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Buses Going to Winston-Salem
- Bus from Durham to Winston-Salem
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- Bus from Windsor to Winston-Salem
- Bus Charlotte - Winston-Salem
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- Bus from Lima to Winston-Salem
- Bus New York City - Winston-Salem
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- Bus from New Haven to Winston-Salem
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Popular routes in this country
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