Bus Tickets from San Ysidro, CA to San Francisco, US

Find affordable bus tickets from San Ysidro, CA to San Francisco, US with flexible options. Book your trip now

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TodaySep 6
TomorrowSep 7
MonSep 8
from US$74
TueSep 9
WedSep 10
from US$62
ThuSep 11
from US$74
FriSep 12
SatSep 13
from US$66

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: September 8 at
    Departure city: San Ysidro
    Departure location: San Ysidro Bus terminal
    Arrival time: September 9 at
    Destination city: San Francisco
    Destination location: 409 Townsend St, SF
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: September 8 at
    Departure city: San Ysidro
    Departure location: San Ysidro Bus terminal
    Arrival time: September 9 at
    Destination city: San Francisco
    Destination location: San Francisco Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus San Ysidro, CA to San Francisco, US: Trip Overview

Average Ticket PriceUS$85
Average Bus Trip Duration12h 55m
Number of daily buses2
Earliest bus departure6:30am
Distance759 km
Latest bus departure7:00pm

San Ysidro to San Francisco Bus

With Busbud, comparing and booking tickets for a bus from San Ysidro to San Francisco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Ysidro to San Francisco.

From cheap bus tickets to more luxurious buses travelling from San Ysidro to San Francisco, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Ysidro, CA - San Francisco, US

  1. What is the distance between San Ysidro and San Francisco?

    San Ysidro and San Francisco are 760 km (471 miles) apart.

  2. What are the departure and arrival locations for buses traveling from San Ysidro to San Francisco?

    Buses departing from San Ysidro Greyhound Bus Station in San Ysidro will take you to Hyde/Beach (Fisherman's Wharf) in San Francisco.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-04
US$73
09-05
US$85
Today
No data
09-07
No data
09-08
US$66
09-09
No data
09-10
US$54
09-11
US$69
busbud logoThe cheapest trip from San Ysidro, CA to San Francisco, US was searched and found on Sep 10, 2025 with a price of US$54

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to San Francisco, US, as early as possible.

You can expect to pay from US$54 to US$95 for a bus ticket from San Ysidro, CA to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$54 which is on 2025-09-10.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Ysidro to San Francisco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Ysidro to San Francisco.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Ysidro to San Francisco that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from San Ysidro to San Francisco while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to San Ysidro, CA by bus?

Bus from San Francisco, US to San Ysidro, CA

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