Bus Tickets from San Francisco, US to San Ysidro, CA

Next departures

Next departures for San Francisco to San Ysidro on September 10
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
San Francisco Bus Station
San Ysidro Bus terminalCheapest
FlixBus + Greyhound Lines, Inc.
409 Townsend St, SF
San Ysidro Bus terminalFastest
FlixBus
409 Townsend St, SF
San Ysidro Bus terminalNo tags
FlixBus + Greyhound Lines, Inc.
409 Townsend St, SF
San Ysidro Greyhound Bus StationNo tags
Greyhound Lines, Inc.
San Francisco Bus Station
San Ysidro Bus terminalNo tags

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Bus San Francisco, US to San Ysidro, CA: Trip Overview

Average Ticket PriceUS$85
Average Bus Trip Duration13h 30m
Number of daily buses5
Earliest bus departure6:30am
Distance760 km
Latest bus departure11:25pm

San Francisco to San Ysidro Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Francisco to San Ysidro.

Bus service from San Francisco to San Ysidro will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to San Ysidro from San Francisco, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip San Francisco, US - San Ysidro, CA

  1. How far is San Francisco from San Ysidro?

    San Francisco and San Ysidro are 760 km (471 miles) apart.

  2. What are the departure and arrival locations for buses traveling from San Francisco to San Ysidro?

    Buses departing from Hyde/Beach (Fisherman's Wharf) in San Francisco will take you to San Ysidro Greyhound Bus Station in San Ysidro.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-07
US$87
09-08
US$73
Today
US$63
09-10
US$82
09-11
US$77
09-12
US$85
09-13
US$68
09-14
No data
busbud logoThe cheapest trip from San Francisco, US to San Ysidro, CA was searched and found on Sep 9, 2025 with a price of US$63

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to San Ysidro, CA, as early as possible.

You can expect to pay from US$63 to US$141 for a bus ticket from San Francisco, US to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at US$68 which is on 2025-09-13.

Usually Greyhound, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Francisco to San Ysidro but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from San Francisco to San Ysidro, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Francisco to San Ysidro.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Francisco to San Ysidro.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to San Francisco, US by bus?

Bus from San Ysidro, CA to San Francisco, US

Why choose Busbud?

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