Bus Tickets from San Diego, CA, US to Harrisburg

Previously seen trips

Next departures for San Diego to Harrisburg on October 2
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
San Diego (Old Town-FlixBus)
Harrisburg Bus StationNo tags
FlixBus + Greyhound
UCSD Health La Jolla Station
Harrisburg Bus StationNo tags
Greyhound
Greyhound Bus Stop
Harrisburg Bus StationNo tags
Greyhound + FlixBus
5716 Hardy Ave
Harrisburg Bus StationNo tags
Greyhound
Greyhound Bus Stop
Harrisburg Bus StationNo tags

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from San Diego to Harrisburg

Bus
Average PriceUS$214 - US$332Average Duration2d 19h
92kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$422 - US$462Average Duration2d 19h
334kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from San Diego to Harrisburg

Among the sustainable travel choices, the bus stands out as a good way to reach Harrisburg. The journey takes about 2 days, 19 hours 35 minutes, and with fares starting at just US$214, it presents an excellent value for a comfortable ride.

10bus per day
2d 19hAverage Duration
US$214Cheapest ticket
92kgCO₂ emissions

Bus San Diego, CA, US to Harrisburg: Trip Overview

Average Ticket PriceUS$293
Average Bus Trip Duration2d 19h
Number of daily buses10
Earliest bus departure6:45am
Distance3666 km
Latest bus departure7:35pm

San Diego to Harrisburg Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Diego to Harrisburg.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Diego to Harrisburg.

From cheap bus tickets to more luxurious buses travelling from San Diego to Harrisburg, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Diego, CA, US - Harrisburg

  1. What is the travel distance from San Diego to Harrisburg?

    The distance between San Diego and Harrisburg is approximately 3668 km (2275 miles).

  2. What are the departure and arrival locations for buses traveling from San Diego to Harrisburg?

    Buses departing from Mission Valley Sheraton in San Diego will take you to Harrisburg Bieber Greyhound Station in Harrisburg.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-30
US$206
10-01
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Today
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10-03
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10-04
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10-05
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10-06
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10-07
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busbud logoThe cheapest trip from San Diego, CA, US to Harrisburg was searched and found on Sep 30, 2025 with a price of US$206

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Harrisburg, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Diego to Harrisburg but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Diego to Harrisburg.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to Harrisburg that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from San Diego to Harrisburg, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from San Diego, CA, US to Harrisburg?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Diego, CA, US by bus?

Bus from Harrisburg to San Diego, CA, US

You can also go to Harrisburg by train

Train from San Diego, CA, US to Harrisburg

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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