Bus from Salisbury, NC, US to St. Louis: Tickets & Schedules

Previously seen trips

Next departures for Salisbury to St. Louis on December 10
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
Bus
Salisbury (Citgo Fast Stop)
Gateway StationNo tags
GreyhoundBus
Salisbury (Citgo Fast Stop)
Gateway StationNo tags
FlixBus + Greyhound
Bus
Salisbury (Citgo Fast Stop)
Gateway StationNo tags
GreyhoundBus
Salisbury (Citgo Fast Stop)
Gateway StationNo tags
Greyhound + FlixBus
Bus
Salisbury (Citgo Fast Stop)
Gateway StationNo tags

Compare 2 ways to go from Salisbury to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 23 hours 5 minutes, and with fares starting at just $176, it presents an excellent value for a comfortable ride.

2bus per day
23h 5mAverage Duration
926 kmDistance
23kgCO₂ emissions
Average Price$176 - $462Average Duration23h 5m
23kg CO₂e
Average Price$405 - $3,270Average Duration1d 13h
84kg CO₂e

Frequently asked questions about travelling from Salisbury, NC, US to St. Louis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Salisbury to St. Louis?

    The cheapest bus tickets from Salisbury to St. Louis start from $176. The average price for this route is around $234. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Salisbury to St. Louis?

    The average bus travel time from Salisbury to St. Louis is 23h 5m, covering a distance of 926 km. The quickest bus can get you there in 21h 50m and is operated by Greyhound.

  3. Which bus companies service the Salisbury to St. Louis route?

    Several major bus companies operate on this route with 2 buses available per day.

  4. What are the earliest and latest departure times for the bus from Salisbury to St. Louis?

    The earliest bus departs from Salisbury to St. Louis at 6:15am. And the latest bus departs at 7:05pm.

  5. What are the CO₂ emissions for the bus trip from Salisbury to St. Louis?

    A bus trip from Salisbury to St. Louis generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12-08
No data
12-09
$262
Today
No data
12-11
No data
12-12
No data
12-13
No data
12-14
No data
12-15
No data
busbud logoThe cheapest trip from Salisbury, NC, US to St. Louis was searched and found on Dec 9, 2025 with a price of $262

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salisbury, NC, US to St. Louis, as early as possible.

What's the cheapest way to go from Salisbury, NC, US to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

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