Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Salisbury (Citgo Fast Stop) | Gateway Station | Cheapest | ||||
 | Bus | Salisbury (Citgo Fast Stop) | Gateway Station | Fastest |
Last refresh of the prices: Yesterday at 22:19 EST.
Compare 2 ways to travel from Salisbury to St. Louis
Among the sustainable travel choices, the Bus stands out as a good way to reach St. Louis. The journey takes about 22 hours 10 minutes and with fares starting at just £114, it presents an excellent value for a comfortable ride.
Where are the popular stops in Salisbury and St. Louis?
Compare bus companies
Based on 87521 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at £114
Frequently asked questions about travelling by bus from Salisbury, NC, US to St. Louis
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Salisbury to St. Louis?
The cheapest coach tickets from Salisbury to St. Louis start from £114. The average price for this route is around £123. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Salisbury to St. Louis?
The average bus journey time from Salisbury to St. Louis is 22h 10m, covering a distance of 574 miles. The fastest bus can take you there in 22h 10m and is operated by Greyhound.
Which bus companies service the Salisbury to St. Louis route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Salisbury to St. Louis?
The earliest bus departs from Salisbury to St. Louis at 11:05. And the latest bus departs at 18:45.
What are the CO₂ emissions for the bus trip from Salisbury to St. Louis?
A bus journey from Salisbury to St. Louis produces an estimated 23 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Salisbury, NC, US to St. Louis was searched and found on 8 Feb 2026 with a price of £152To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salisbury, NC, US to St. Louis as early as possible.
You can expect to pay from £152 to £152 for a bus ticket from Salisbury, NC, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at £152, which is on 2026-02-08.
What's the cheapest way to go from Salisbury, NC, US to St. Louis?
The Bus is the cheapest travel choice for this destination
